Project Grant R01ES038862
- This Project Grant from the U.S. Geological Survey, under the Assistance to State Water Resources Research Institutes federal program (CFDA 15.805), provides $500,000 to the University of Wisconsin-Madison from December 2022 through December 2025. The funding supports research to quantify per- and polyfluoroalkyl substances (PFAS) bioaccumulation and potential health impacts in economically important plants and animals associated with aquatic ecosystems in ceded territories of the Great Lakes...
- The National Institute of Environmental Health Sciences awarded North Carolina State University $4,233,899 under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) on August 1, 2026, to evaluate per- and polyfluoroalkyl substances (PFAS) exposure and associated metabolic health effects across three North Carolina communities with contaminated drinking water supplies. The research examines PFAS-induced dyslipidemia and obesity in approximately 1,000...
- The National Institute of Environmental Health Sciences awarded Silent Spring Institute, Inc., $154,700 on August 28, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to assess associations between per- and polyfluoroalkyl substance (PFAS) exposure from drinking water and hypertension and blood pressure among adults and children. The project will analyze measured and historically reconstructed serum PFAS concentrations in relation to blood...
- The National Institute of Environmental Health Sciences awarded The University of Iowa $427,625 under Project Grant R21ES038702 on July 7, 2026, to investigate neurotoxic effects of per- and polyfluoroalkyl substance (PFAS) mixtures on memory and gene expression in animal models. The research employs multi-omics investigation to assess changes in brain region-dependent gene expression relevant to memory in mice following exposure to a human-relevant PFAS mixture and to identify individual PFAS...
- The Department of Agriculture National Institute of Food and Agriculture awarded the University of Wisconsin System (University of Wisconsin–Green Bay) $750,000 on September 1, 2026, under the Capacity Building for Non-Land Grant Colleges of Agriculture program (CFDA 10.326) to evaluate practical soil treatment approaches that use biochar to bind PFAS (per- and polyfluoroalkyl substances) and prevent movement into groundwater and crops. The project addresses contamination risks from land...
- The National Institute of Environmental Health Sciences awarded The Pennsylvania State University $2.864 million on April 4, 2026, under the Environmental Health program (CFDA 93.113) to investigate how per- and polyfluoroalkyl substances (PFAS) alter microbial function and drive disease progression through disruption of the host-gut microbiome axis. The research addresses early-life PFAS exposure, a particular concern because developmental periods represent a critical window of vulnerability...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Massachusetts Lowell $157,437 under the Environmental Health program (CFDA 93.113) on May 10, 2025, for a two-year project concluding May 9, 2027. This Project Grant supports research defining the urinary, biliary, and fecal excretion pathways of diverse per- and polyfluoroalkyl substances (PFAS) and investigating the impact of dietary fiber on PFAS elimination. The research...
- This $963,000 Project Grant award from the National Institute of Standards and Technology (NIST) under the Congressionally-Identified Projects program (CFDA 11.617) will enable the University of Wisconsin-Madison (UW-Madison) to advance its PFAS Center of Excellence analytical capabilities. The grant will fund the acquisition of a liquid chromatograph high-resolution mass spectrometer (LC-HRMS) and an automated solid phase extractor (Auto-SPE) for the university's Core for Advanced Water...
- The National Institute of Environmental Health Sciences awarded the University of Wisconsin–Madison $153,282 on October 1, 2025, under the Environmental Health program (CFDA 93.113) to support research on the role of estrogen receptor beta in polychlorinated biphenyls impacts on bladder function. The research investigates how in utero and lactational exposure to human-relevant polychlorinated biphenyl mixtures alters urinary voiding function in mice through estrogen receptor beta activation...
- The National Institute of Environmental Health Sciences awarded Virginia Commonwealth University $426,938 on July 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate how lipid transport proteins mediate the biodistribution and accumulation of per- and polyfluoroalkyl substances (PFAS) in human tissues and cells. The three-part research program develops fluorescent and nuclear magnetic resonance binding assays to screen five representative lipid transport proteins against...
The National Institute of Environmental Health Sciences awarded the University of Wisconsin - Madison $3,343,688 on September 1, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to examine pathways of per- and polyfluoroalkyl substances (PFAS) exposure and their impacts on hyperlipidemia in a rural community impacted by land spreading of biosolids and sludge. The research addresses three gaps in PFAS science. The study will examine how lipid metabolism mediates PFAS health effects across a broader range of legacy and emerging PFAS compounds beyond the handful studied in prior human health research, despite over 10,000 PFAS existing. It will characterize precursor compounds such as polyfluoroalkyl phosphate esters (PAPEs) that industry has substituted for legacy PFAS and their bio-transformation into perfluorooctanoic acid (PFOA), a classified carcinogen. The project will also generate rural biomonitoring data, as existing data come predominantly from occupational and urban settings and overlook exposure pathways in agricultural areas where PFAS accumulates in soil, groundwater, surface water, and locally produced food. Wisconsin provides the study setting, where private wells contain some of the nation's highest PFAS levels (exceeding 36,000 parts per trillion), with contamination linked to biosolid and papermill sludge land spreading. The performance period runs from September 1, 2026, through August 31, 2030, with work performed in Madison, Wisconsin.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.3m | 8/31/26 |