Project Grant R01DK146952
- Federal Project Grant Award Summary George Washington University received a $129,990 Project Grant award dated August 31, 2026, from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports investigator-initiated research investigating nerve fiber-associated macrophages in prostate development, with performance through February 28, 2029. The research aims to...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the University of Pittsburgh a $2.48 million Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) on September 15, 2025, with completion targeted for August 31, 2029. The research project investigates ZC3H4-driven prostate tissue remodeling mechanisms underlying benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) in aging men. The...
- Federal Grant Award Summary Stanford University received a $534,802 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective February 5, 2026, with a completion date of November 30, 2029. The award supports biomedical research to advance understanding of benign prostatic hyperplasia (BPH) pathogenesis and develop targeted prevention and treatment...
- Federal Grant Award Summary Mayo Clinic received a $203,676 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective August 1, 2025, through July 31, 2028. The award supports research to evaluate patient preferences and priorities regarding benign prostatic hyperplasia (BPH) surgical treatment options. The project will identify perioperative factors...
- Federal Project Grant Award Summary Beth Israel Deaconess Medical Center, Inc. (BIDMC) received a $739,141 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on April 22, 2026, with a completion date of March 31, 2031. The research investigates the role of adiponectin signaling in regulating bladder function and lower urinary tract symptoms (LUTS),...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $138,272 Project Grant to The Leland Stanford Junior University, effective April 1, 2026 through March 31, 2031, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research investigating the molecular mechanisms of benign prostatic hyperplasia (BPH), a prevalent condition in men with an estimated annual economic...
- Federal Grant Award Summary Beth Israel Deaconess Medical Center, Inc. received a $765,701 Project Grant award dated September 9, 2025, from the National Institute of Diabetes and Digestive and Kidney Diseases under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds basic biomedical research to map mechanosensory neural circuits controlling bladder sensation and urination through the completion date of May 31, 2030. The research will employ...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Baylor College of Medicine a $3,005,541 Project Grant on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the mechanisms underlying age- and sex-dependent changes in urinary bladder immunity. The research focuses on recurrent urinary tract infections (RUTIs) in elderly women, which affect 25–50% of the...
- Federal Project Grant Summary The University of Illinois received a $1.62 million Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded July 1, 2025, with a completion date of April 30, 2030. This research project investigates the molecular mechanisms by which growth hormone (GH) and STAT5-regulated transcription factors protect the liver from...
- Federal Grant Award Summary The University of Michigan received a $580,568 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 1, 2025, through June 30, 2029. This award supports biomedical research investigating the role of CD45 (a tyrosine phosphatase) in regulating neutrophil function during intestinal inflammation, with particular...
Endeavor Health Clinical Operations (Northshore University Healthsystem Research Institute Division), located in Evanston, Illinois, received a $529,928 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, effective May 1, 2026 through March 31, 2031, supports basic biomedical research focused on understanding the mechanisms of benign prostatic hyperplasia (BPH) in aging men. The research investigates the role of lipid-rich triggering receptor expressed on myeloid cells 2 (TREM2)-expressing macrophages in promoting BPH and lower urinary tract symptoms (LUTS). The project will examine how lipid accumulation in TREM2+ macrophages contributes to prostatic hyperplasia through alterations in lipid metabolism and decreased production of anti-inflammatory proteins. Research activities will employ both primary macrophage models and transgenic mouse models to elucidate mechanistic pathways and evaluate TREM2+ macrophages as potential therapeutic targets for BPH management, with anticipated outcomes advancing understanding of inflammation-driven prostatic disease progression.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $529.9k | 5/4/26 |