Opioid and SUD data enclave (o-sudden): bringing real-time data to the opioid crisis
Active Project Grant Awarded Last action
- Award ID
- R01DA057668
- Recipient
-
The Ohio State University UEI DLWBSLWAJWR1
- Awarding agency
-
National Institute on Drug Abuse
National Institutes of Health, Department of Health and Human Services
- Obligated
- $7,030,857
Award facts
- Assistance listing
- 93.279 Drug Use and Addiction Research Programs
- Completion date 82% complete
- Originally
- Place of performance
- Columbus, OH 43210, USA
Award details come from USAspending.gov.
Description
- Abstract
- The widespread availability of synthetic opioids (fentanyl) has fueled the rapidly rising rates of unintentional over dose (OD) fatalities. Policy makers, state and local agencies, and investigators have focused on the ohio experience as a bellwether for the experiences of other states because of the representativeness of ohio's demographics. The lack of timely geospatially-linked longitudinal data sources has impeded the ability of communities and state agencies to pivot allocation of resources to regions where they are needed most. Limited integration of environmental risk factors such as sociodemographic characteristics fail to support identification of new targets for intervention or new approaches to emerging threats from changes in local drug supply. We believe that agile data systems and informatics tools that can be used to demonstrate the utility of predictive analytics and machine intelligence approaches on how to enable data-driven decision making will ultimately prove translatable across the country and diverse localities. Our proposed opioid and substance use disorder data enclave (o-sudden) will provide a novel and transformative approach to support rigorous and reproducible research on the opioid and substance use crises. O-sudden will fill several existing gaps in data infrastructure and prediction models that include machine learning, geospatial analyses, and community context. The specific aims for o-sudden are as follows: aim 1: data linkage with establishment of o-sudden. We will develop a geospatially-sensitive, individual-level secure data lake that integrates multiple disparate data sources that meets the requirement of a coded-limited set under hipaa. New data sources include real-time individual-level longitudinal data from urine drug testing (UDT) and community contextual data based on the ohio opportunity index, an area-level social determinants of health developed and used by our team. We will develop query and use tools for data harmonization and integration, prepare and release data sets for dissemination and secondary data analyses; and facilitate secondary use of related administrative data to generate evidence that informs targeted opioid interventions. Aim 2: develop predictive models and surveillance algorithms. Geospatial and machine learning will be used to model the contribution of opioid, cocaine, and stimulant use on OD, OD death and opioid use disorder/substance use disorder (OUD/SUD); temporal relationship of real time data including UDT and demographic and contextual variables to identify high- risk populations and subpopulations or geographic locales. We will validate model performances and predictive power and then disseminate surveillance and forecasting algorithms through the o-sudden portal for end-user access. Aim 3: deploy a human-centered platform and actional informatics. Applying CO-design principles with a human-centered work group consisting of end-user stakeholders (community, researchers, and state policy makers/agencies), we will develop and deploy an end-user tailored portal and effective user-friendly tools to provide actionable insights to inform opioid treatment and targeted harm reduction strategies.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $693,676 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $681,213 | |
| Amendment | $681,213 | |
| Amendment | $681,213 | |
| Amendment | $186,244 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $2,053,649 | |
| Original award | $2,053,649 |
Show all 18
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Millennium Health LLC | $382,286 |
Quick answers
Who received award R01DA057668?
R01DA057668 was awarded to The Ohio State University by National Institute on Drug Abuse (National Institutes of Health) on September 30, 2022.
How much is award R01DA057668 worth?
$7,030,857 has been obligated on R01DA057668.
On GovTribe
See this award's full record
- Every transaction and subaward
- The recipient's other awards and teaming partners
- Similar grant awards
- Ask GovTribe AI about this award