Soar: smartphones for opioid addiction recovery
Active Project Grant Awarded Last action
- Award ID
- R01DA054220
- Recipient
-
New York University UEI M5SZJ6VHUHN8 Part of New York University
- Awarding agency
-
National Institute on Drug Abuse
National Institutes of Health, Department of Health and Human Services
- Obligated
- $13,773,834
Award facts
- Assistance listing
- 93.279 Drug Use and Addiction Research Programs
- Completion date 89% complete
- Originally
- Funding
-
- $11,773,090.00 Federal
- $2,000,744.00 Non-federal
- Place of performance
- New York, NY 10016, USA
Award details come from USAspending.gov.
Description
- Abstract
- Over 2 million americans suffer from opioid use disorder (OUD) and another 9 million misuse opioids. Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus recently become a major nida policy goal. Elevated reuse rates not only compromise treatment effectiveness, but this behavior predicts, and likely drives, treatment dropout. With the support of a nida basic science R01, we developed a set of easy-to-use instruments that predict opioid reuse events with about twice the accuracy of any existing tool. The 5-minute battery we developed indicates the numerical probability that a patient will reuse illicit opiates within the next 7-10 days. In a pilot cohort, we successfully migrated this battery to a commercial smartphone platform, and demonstrated 100% retention and >85% compliance (median compliance > 95%) over a use period of up to 4 months. In a survey of our largely homeless moud patients we found that 85% already had smartphones and data contracts appropriate for using this platform as a part of their treatment. In a survey of OUD treatment physicians, we found that our system and the reuse prediction IT provides, was both highly desirable and usable as implemented. Finally, we found in a reanalysis of data from CTN-0051 that dynamic dosing of this very kind reduces relapse rates. Our primary goal in this mid-scale clinical trial is to test the hypothesis that clinicians who use the output of our mobile system to adjust buprenorphine and methadone dosing achieve lower opiate reuse rates than physicians who provide care-as-usual. Our secondary goal is to examine the usability and desirability of this solution for clinicians with an eye to usability and large-scale deployment. Our third and final goal is to measure the cost-effectiveness of this solution from multiple perspectives. If we are successful IT will be possible to employ an algorithmic and measurement-based approach to OUD treatment with methadone and buprenorphine which reduces reuse rates and relapse rates amongst OUD patients.
Transactions
| Action | Federal | Non-federal | Date |
|---|---|---|---|
| Amendment | $0 | $0 | |
| Amendment | $140,800 | $0 | |
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| Amendment | $970,164 | $0 | |
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| Amendment | $158,414 | $0 | |
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| Amendment | $1,011,393 | $0 | |
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| Amendment | $1,011,246 | $0 | |
| Amendment | $1,010,866 | $0 | |
| Amendment | $1,010,866 | $1,010,866 | |
| Amendment | $0 | $0 | |
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| Amendment | $989,878 | $0 | |
| Original award | $989,878 | $989,878 |
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Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| University Of Maryland Baltimore County | $140,800 | |
| Rutgers The State University Of New Jersey | $666,021 | |
| Friends Research Institute, Inc. | $72,398 | |
| Startcare, Inc. | $49,748 | |
| University Of Maryland Baltimore County | $141,039 | |
| Rutgers The State University Of New Jersey | $222,007 | |
| The Trustees Of Columbia University In The City Of New York | $47,569 | |
| Cornell University | $59,168 | |
| Friends Research Institute, Inc. | $61,539 | |
| The Trustees Of Columbia University In The City Of New York | $141,665 | |
| Rutgers The State University Of New Jersey | $666,021 |
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Quick answers
Who received award R01DA054220?
R01DA054220 was awarded to New York University by National Institute on Drug Abuse (National Institutes of Health) on August 15, 2021.
How much is award R01DA054220 worth?
$13,773,834 has been obligated on R01DA054220: $11,773,090 in federal funding and $2,000,744 in non-federal funding.
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