Project Grant R01AG108198
- The National Institute on Aging awarded Mayo Clinic $729,906 on September 3, 2026, under the Aging Research program (CFDA 93.866) to investigate the neurobiological substrates of falls in cognitively unimpaired older adults. The research uses dual-task paradigms that simultaneously engage motor and cognitive brain systems to characterize subclinical gait impairment patterns among cognitively unimpaired individuals who experience falls. The study assesses how gait impairment relates to...
- The National Institute on Aging awarded Hebrew Rehabilitation Center $318,000 on August 18, 2026, under the Aging Research program (CFDA 93.866) to conduct a pilot study of home-based dual-task gait assessment in older adults at risk of dementia. The project will recruit 60 ambulatory adults aged 65 and older—30 with mild cognitive impairment and 30 age- and sex-matched controls—to use a smartphone-based gait application for daily assessments in their homes over a two-week baseline period,...
- The National Institute on Aging awarded $665,690 to the University of Florida on July 1, 2026, under the Aging Research program (CFDA 93.866) to develop and sustain G-CAR2E (Gerontology Centers to Aid Remote Research in Elders), a mobile software platform for remote monitoring of episodic health events—falls, injuries, illnesses, and hospitalizations—in older adults using smartphone-based continuous data capture and a research-dedicated app designed with user input. G-CAR2E organizes...
- The National Institute on Aging awarded Rochester Institute of Technology $125,650 on September 15, 2026, under the Aging Research program (CFDA 93.866) to develop and evaluate a smartphone-based digital coaching system for fall prevention in stroke survivors. The project delivers three core products: a prototype digital coaching application providing personalized reminders, exercise prompts, and safety guidance co-designed with stroke survivors, caregivers, and physical therapists; pilot...
- The National Institute on Aging awarded $691,763 to the Rehabilitation Institute of Chicago (doing business as Shirley Ryan AbilityLab) on August 1, 2026, under the Aging Research program (CFDA 93.866) to evaluate the effectiveness of a wearable hip airbag equipped with a stroke-specific pre-impact fall detection algorithm in older adults with stroke. The project will assess whether the wearable airbag accurately deploys during falls, reduces hip injuries, decreases fear of falling, and...
- The National Institute on Aging awarded the University of Florida $597,264 on August 15, 2026, under the Aging Research program (CFDA 93.866) to develop and deploy the Automated Neurodegeneration Index (ANDI), a machine learning software tool that quantifies neurodegeneration severity in at-risk populations for Lewy body disease. ANDI uses routine 3 Tesla diffusion MRI scans and an automated free-water algorithm to generate a standardized, individual-based neurodegeneration index scaled from 0...
- The National Institute on Aging awarded the University of Florida $439,739 on June 1, 2026, under the Aging Research program (CFDA 93.866) to investigate biobehavioral signatures of repetitive head impacts at the intersection of aging and Alzheimer's disease. The award funds a longitudinal multi-site study examining fluid biomarkers, neuroimaging, and cognition in aging adults with and without prior repetitive head impacts (RHI). The research addresses how RHI—exposure from contact sports,...
- The National Institute on Aging awarded Colorado State University $231,000 on September 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a pilot clinical trial assessing the feasibility, acceptability, and efficacy signal of a real-life dual-task training intervention for older adults at risk of falling. The study compares a six-week real-life dual-task training intervention (REAL-DTT) with an evidence-based fall prevention intervention (FallStalk). REAL-DTT delivers...
- The National Institute on Aging awarded Boston University Medical Campus $110,228 in project grant funding on February 7, 2027, to develop and validate a novel cellular model of entorhinal cortex layer II vulnerability in Alzheimer's disease under the Aging Research program (CFDA 93.866). The project will develop in vitro models using induced pluripotent stem cells (iPSCs) and direct fibroblast conversion to generate entorhinal cortex layer II (ECII)-like neurons for studying Alzheimer's disease...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Florida's Division of Sponsored Research $405,045 under the Aging Research program (CFDA 93.866) for a two-year project period beginning August 1, 2025 and concluding July 31, 2027. This project grant funds research investigating the neurophysiology of locomotor adaptation and freezing of gait (FOG) in Parkinson's disease (PD). The research will deliver scientific knowledge regarding the neural...
The National Institutes of Health Office of the Director awarded Florida Atlantic University $225,735 for Project Grant R01AG108198 on September 1, 2026, under the Aging Research program (CFDA 93.866). The project develops artificial intelligence models that use smartphone video to assess fall risk in older adults through analysis of the Timed Up and Go test, a clinical assessment of gait and balance. Aim 1 creates 3D pose estimation models integrating biomechanical constraints, transformer-based temporal fusion, and depth-aware loss functions to extract gait and balance markers from smartphone video, validated against lab-based ground-truth data from 100 older adults. Aim 2 develops interpretable, transformer-based deep survival models to predict monthly fall probabilities and generate personalized, time-specific fall-risk predictions. The approach eliminates the need for costly lab-based measurement tools such as motion-capture systems, depth cameras, or pressure mats. Work is performed in Boca Raton, Florida. The period of performance extends from September 1, 2026 through May 31, 2030. The Aging Research program supports biomedical, social, and behavioral research directed toward understanding the aging process and diseases of older adults, with particular emphasis on Alzheimer's disease and related dementias. This is a Project Grant, a standard NIH research award mechanism.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $225.7k | 9/2/26 |