Project Grant P50CA302567
- The National Cancer Institute awarded Emory University $646,181 on April 2, 2026, under the Cancer Biology Research program (CFDA 93.396) to investigate how clonal hematopoiesis mutations drive non-small cell lung cancer development through immune suppression. The research examines the mechanisms by which clonal hematopoiesis—an age-related condition affecting over 20 percent of individuals aged 70 and older—promotes lung cancer by fostering an immunosuppressive tumor microenvironment, with...
- The National Cancer Institute awarded Emory University $572,378 through a Cancer Biology Research Project Grant (CFDA 93.396, R01CA299279) on May 1, 2026. The recipient will investigate metabolic regulation of dormancy in disseminated non-small cell lung cancer (NSCLC) subpopulations, specifically examining how collective invasive cell packs transition from micrometastatic to macrometastatic lesions. The research applies an image-guided genomics approach to study differential genetic...
- This federal Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) provides $568,687 to Emory University to develop novel radiogenomic tools for predicting outcomes for small cell lung cancer patients treated with chemoimmunotherapy. The project, with a performance period from February 1, 2024 to January 31, 2027, aims to advance scientific knowledge and improve clinical outcomes in this patient population through...
- The National Cancer Institute awarded Emory University $682,730 on August 13, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a patient-centered value assessment informing value-based insurance design models for outpatient specialty palliative care in advanced cancer. The project, titled UNCOVER-PC: Uniting Novel Concepts of Value to Enhance Reform in Palliative Care, addresses low uptake of specialty palliative care among advanced cancer patients—only 10...
- The National Cancer Institute, a component of the Department of Health and Human Services National Institutes of Health, awarded Emory University $149,190 on January 21, 2026, under the Cancer Research Manpower program (CFDA 93.398) to support formative research on faith-based lung cancer screening promotion. The award funds trainee Ms. Anderson to conduct research on the readiness of faith communities in Georgia to promote lung cancer screening, with particular focus on African American...
- Federal Project Grant Award Summary Emory University received a $158,899 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) awarded June 20, 2025, with completion targeted for May 31, 2027. This award supports the development of an innovative Simultaneous Intensity Energy Modulation and Compensation (SIEMAC) optimization platform and integrated quality assurance (QA) system for conformal flash proton therapy treatment of central lung...
- The National Cancer Institute awarded Emory University $100,228 under the Cancer Research Manpower program (CFDA 93.398) on December 1, 2026, to support research training in biomedical careers relevant to the National Cancer Program. The award funds investigation of PYCR phosphorylation in chemoimmunotherapy resistance, specifically examining how fibroblast growth factor receptor 1 (FGFR1) phosphorylates proline cycle regulatory enzymes (PYCR1 and PYCR2) and confers resistance to combined...
- The National Institutes of Health National Cancer Institute awarded the University of Virginia $730,007 on August 1, 2026, under the Cancer Biology Research program (CFDA 93.396) to identify N6-methyladenosine (M6A) marks and genes influencing lung cancer risk. The award funds a five-year project (August 1, 2026 through July 31, 2031) combining genetic epidemiology, multi-omics analysis, and in vitro studies to characterize M6A's role in lung tumorigenesis. The work includes conducting an...
- The National Cancer Institute, part of the Department of Health and Human Services National Institutes of Health, awarded Emory University $636,358 on June 18, 2026, under the Cancer Treatment Research program (CFDA 93.395) to conduct basic and applied research targeting VIP-VPAC signaling pathways as a therapeutic strategy to reverse immune exclusion in pancreatic ductal adenocarcinoma and enhance immunotherapy response. The award funds three specific research aims: identifying primary...
- The National Cancer Institute awarded The University of Texas MD Anderson Cancer Center $192,224 on September 1, 2026, under the Cancer Research Manpower program (CFDA 93.398) to support research on secreted peptides as biomarkers and effectors of neuroendocrine transformation in lung cancer. The funded work investigates pulmonary neuroendocrine cell (PNEC) biology and the histologic transformation of lung adenocarcinoma to small cell lung cancer. The research employs a genetically engineered...
The National Cancer Institute awarded Emory University $2.194 million under the Cancer Centers Support Grants program (CFDA 93.397) on August 18, 2026, to support the Emory Lung Cancer SPORE (Specialized Program of Research Excellence). The award funds a revised research program focused on three specific aims: examining novel inhibitory molecules expressed by stem-like CD8 T cells and conducting a clinical trial to evaluate a novel immunotherapy combination approach for advanced non-small cell lung cancer (NSCLC); utilizing an artificial intelligence-informed systems biology approach to predict outcomes in stage III NSCLC patients, leveraging a recently completed phase III ECOG-ACRIN clinical trial; and interrogating a noncanonical mitochondrial signaling pathway that mediates lung cancer metastasis. The program builds on findings from the current SPORE, first funded in 2019, and brings together a multidisciplinary team of clinical oncologists, immunologists, computational scientists, drug discovery experts, and translational investigators to address critical questions aimed at improving outcomes for patients with NSCLC. Performance occurs in Atlanta, Georgia. The period of performance extends through July 31, 2031. Emory University's Office of Sponsored Programs is the recipient.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.2m | 8/18/26 |