Project Grant N62909131N259

This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $449,999 to Trustees of Boston University to develop a novel class of wireless, free-floating biosensors that integrate electronic and biological sensing elements. The goal is to provide real-time, in situ monitoring of microbial dynamics within industrial fermentation environments. The biosensors combine engineered microbes that emit light in response to stress with embedded electronics to...

This $375,000 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of redox-based bioelectronics through the Semisynbio-III award to the University of Maryland, College Park. The three-year project will advance four technological areas to create communicating microbial cells and decision-making cells that can be instructed by electric inputs to perform logic operations by writing to genomes or adjusting consortium populations....

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will develop living biosensors capable of detecting and analyzing DNA at the single-base level without requiring sample purification or equipment. The $565,614 award, effective April 5, 2025 through March 31, 2029, will enable the University of California, San Diego to create...

This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $500,000 in funding to The Regents of the University of Colorado to develop a suite of fluorescent RNA-based biosensors for monitoring metabolites in the methionine cycle of one-carbon metabolism in live cells. The project aims to create a "plug-and-play" toolkit of biosensors that can be used to study the dynamics and flux of central metabolites involved in regulating...

The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $647,750 Project Grant to Princeton University under the Biological Sciences grant program (CFDA 47.074) to develop a closed-loop control system for regulating microbial communities. The project aims to integrate optogenetic controls and metabolite biosensing to dynamically modulate the composition and productivity of synthetic microbial communities for the production of valuable chemicals. The...

This $650,000 Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) supports the development of engineered microbial sensors for assessing water quality. The primary objective is to create new low-cost sensing systems that can detect chemicals in water throughout the water cycle, including wastewater treatment, drinking water, industrial use, and stormwater discharges. The project employs a convergence research...

This $450,000 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to The Johns Hopkins University supports the development of a new "dual-series gate" organic electrochemical transistor (DS-OECT) biosensor technology. The key objectives include material synthesis, device fabrication, computer modeling, and biological fluid analysis to create a highly sensitive and stable sensor capable of reliably detecting protein biomarkers for various...

This National Science Foundation (NSF) Biological Sciences grant award provides $2,225,964 to the Georgia Tech Research Corporation (Georgia Tech) to develop a novel biosensing platform called "protocell communities" that can be used for rapid, low-cost medical diagnostics. The project aims to create a tool that can diagnose medical conditions by detecting and integrating multiple indicator molecules, addressing limitations of single-analyte diagnostics. The protocell technology uses...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $450,000 Project Grant to the Texas A&M Engineering Experiment Station (Tees) to develop an injectable, grain-of-rice size glucose biosensor for continuous blood sugar monitoring. The key products or services to be provided under this 3-year grant include: Developing an injectable glucose biosensor comprised of a self-cleaning membrane and a near-infrared fluorescence...

Biomesense Inc. received a $883,212 Project Grant award from the National Institutes of Health's National Center for Advancing Translational Sciences to develop a novel biosensor to accelerate investigations of the gut microbiome. The grant will support validating the microbial lysis and DNA isolation functions of a prototype biosensor over a 6-month period ending December 31, 2021. The biosensor is intended to enable dense, time-longitudinal sampling of participants' gut microbiomes in their...