Project Grant K99HD121969
- The National Institute of Child Health and Human Development awarded University of Massachusetts Boston $515,382 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to support research on cellular regulation of pattern in regenerating limb tissue. The research examines how anterior and posterior limb cells direct regeneration of precisely the missing structures in Mexican axolotl limbs, using spatial transcriptomics and in vivo regenerative...
- The National Institute of Child Health and Human Development awarded Oregon Health & Science University $237,660 on January 1, 2026, under the Child Health and Human Development Extramural Research (CFDA 93.865) program to conduct research dissecting neural stem cell states during regeneration using zebrafish and planarian models. The work investigates how neural stem cells regenerate lost neurons following central nervous system injury. The recipient will validate transcriptomic data...
- The National Institute of Child Health and Human Development awarded the University of California, Santa Barbara $123,957 on September 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) for research into how mechanical forces coordinate cell movements during vertebrate gastrulation, specifically examining the Spemann-Mangold organizer's role in establishing germ layers and embryonic axes. The funded research develops and applies...
- The National Institute of Child Health and Human Development awarded The Medical College of Wisconsin, Inc., $639,854 on July 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate mechanically sensitive regulators of human amnion and primordial germ cell formation from a common progenitor. The research addresses infertility by examining the molecular basis of defective amnion formation and primordial germ cell (PGC) specification during...
- The National Institute of Child Health and Human Development awarded University of California Irvine $233,528 on September 27, 2025, under the Child Health and Human Development Extramural Research (CFDA 93.865) program to support research on gene regulatory redundancy in mammalian development. The recipient will conduct experimental work to identify distinct transcription factors driving shadow enhancers—redundant non-coding DNA elements that control gene expression during development—and...
- The National Institute of Child Health and Human Development awarded New York University $100,228 on January 1, 2027, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to support research on force transmission through cell-cell and cell-matrix interactions in bilayered epithelia during wound healing. The research uses embryonic zebrafish skin as a genetically tractable two-layered epithelium to define the roles of cell-cell and cell-matrix adhesions in...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded Seattle Children's Research Institute (doing business as Seattle Children's Hospital) $516,175 under the Research Infrastructure Programs (CFDA 93.351) on August 1, 2026, to develop transgenic technology in Acomys (spiny mice), a non-traditional mammalian model with naturally evolved adult non-fibrotic regenerative capacity. The recipient will establish whole-animal transgenesis pipelines...
- Federal Project Grant Award Summary Boston Children's Hospital received a $674,620 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025 through August 31, 2027. The award supports investigator-initiated research to elucidate the genetic and developmental basis for coordinated limb growth and proportion regulation. The research employs integrated...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded the Regents of the University of Michigan a $386,100 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) beginning August 4, 2025, with completion targeted for July 31, 2027. This award supports investigator-initiated biomedical research designed to advance understanding of human development and improve child health outcomes. The...
- The National Institute of Child Health and Human Development awarded $249,000 to the University of North Carolina at Greensboro on August 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct research dissecting input-output relationships of developmental bone morphogenetic protein (BMP) signaling. The research program employs quantitative imaging techniques, classical genetics, and biochemical approaches to understand how cells produce...
The National Institute of Child Health and Human Development awarded The Morgridge Institute For Research, Inc., $131,832 on August 21, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to support research on appendage regeneration signaling and transcriptional programs. The award funds investigation into how signaling dynamics, transcriptional output, and physiological cues control regenerative growth in zebrafish dermal appendages, using live imaging, optogenetics, and mathematical modeling to examine how osteoblasts interpret dynamic signals to regenerate tissue. The research quantifies ERK wave dynamics across scale regenerates of variable geometries, develops predictive models linking wave parameters to regenerative outcomes, and employs in vivo optogenetic tools to test model predictions. The work also identifies gene regulatory mechanisms governing tissue-scale regeneration and physiological integration. Performance occurs in Madison, Wisconsin, with a period of performance ending July 31, 2028. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $131.8k | 8/21/26 |