Project Grant HT9425261E361
- Award Summary The Defense Health Agency awarded Beckman Research Institute of the City of Hope a Project Grant totaling $1.1M under the Military Medical Research and Development program (CFDA 12.420) to develop LRRC15-targeted Chimeric Antigen Receptor (CAR) T cell therapy for osteosarcoma. The three-year award, effective June 1, 2026 through May 31, 2029, supports translational research at the Institute's Irwindale, California facility. This project represents targeted immunotherapy development...
- Federal Grant Award Summary The Beckman Research Institute of The City of Hope received a $177,992 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025, through August 31, 2027. This award supports the generation of novel tools for the development of targeted approaches for AL (light-chain) amyloidosis, a rare protein-misfolding disease. Research activities are conducted at the Institute's...
- Federal Grant Award Summary Beckman Research Institute of the City of Hope received a $2.136 million Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2025 through August 31, 2028. The award supports developmental therapeutics research and the investigation of potential treatment strategies targeting RALBP1 (Retinoid-binding Protein 1) for castration-resistant prostate carcinoma. This...
- Federal Project Grant Award Summary The Beckman Research Institute of the City of Hope received a $1.32M Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 15, 2025, with completion targeted for September 14, 2029. The award supports research titled "Targeting Diabetes-Associated Radioresistance to Improve Prostate Cancer Control and Quality-of-Life Outcomes," conducted at the...
- The Department of Defense's Defense Health Agency awarded a $447,612 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to the Beckman Research Institute of the City of Hope. The grant supports the development of a "highly tumor-specific oncolytic virus in combination with a viral protein-target T cell engager for the treatment of triple-negative breast cancer." The award period runs from January 1, 2024 to December 31, 2026. As a nonprofit...
- The Defense Health Agency has awarded a $657,263 project grant under the Military Medical Research and Development program (CFDA 12.420) to the Dana-Farber Cancer Institute, Inc. (d.b.a. DFCI) in Boston, MA. The award, effective September 1, 2024 through August 31, 2027, will support DATA-DRIVEN BIOMARKER-INFORMED DECISION ANALYTICS IN MELANOMA: IMPROVING EFFICACY AND REDUCING TOXICITY OF IMMUNE CHECKPOINT BLOCKADE. Through this grant, DFCI will conduct research to develop data-driven...
- The Defense Health Agency awarded Beckman Research Institute of the City of Hope a $416,217 Project Grant under the Military Medical Research and Development program (CFDA 12.420) on September 30, 2026, with an ultimate completion date of September 29, 2029. The grant supports research on photoacoustic computed tomography (PACT) technology to identify and diagnose axillary lymph nodes in breast cancer patients without requiring surgical intervention. This three-year research initiative leverages...
- Federal Grant Award Summary Dana-Farber Cancer Institute, Inc. received a $4.199 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2026 through August 31, 2030. The award funds the development and optimization of B7-H3 chimeric antigen receptor (CAR) T cells for pediatric and young adult patients with sarcomas and other B7-H3-positive solid tumors. This research initiative represents an...
- The Defense Health Agency (DHA) awarded a $1.297M Project Grant to The University of Texas Southwestern Medical Center under the Military Medical Research and Development program (CFDA 12.420) for a four-year research initiative beginning September 1, 2025. This award supports research to identify immunomodulatory targets of TAZ/SRF (transcriptional cofactors) in sarcomatoid renal cell carcinoma progression. The research deliverables include hypothesis-driven investigations, biomarker discovery,...
- Federal Grant Award Summary Dana-Farber Cancer Institute, Inc. (DFCI) received a $1.12M Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2026, through August 31, 2030. The award supports resource development and research to improve clinical outcomes for blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare hematologic malignancy. As a leading academic cancer research institution affiliated...
The Defense Health Agency (DHA) awarded Beckman Research Institute of The City of Hope a $140,000 Project Grant under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2026 through August 31, 2027. The award supports research focused on "Enhancing TIL Trafficking via Paired Cell Engineering and Lipid Nanoparticle Modulation of the Tumor Microenvironment in Mucosal Melanoma." The research will be conducted at the Institute's facility in Irwindale, California and aims to advance tumor-infiltrating lymphocyte (TIL) cell therapy approaches through combined cellular engineering and lipid nanoparticle technologies to improve therapeutic efficacy in mucosal melanoma treatment. This award aligns with the DHA's broad portfolio supporting investigator-initiated biomedical research addressing Service Member health and battlefield medicine. The grant supports Beckman's core research mission in cancer immunology and translational medicine, building upon the Institute's established track record of receiving federal funding for innovative immunotherapy and CAR T cell development initiatives. The 12-month project period is consistent with typical DHA award structures, which generally range from three to four years depending on scope and funding priorities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $140.0k | 6/29/26 |