Project Grant HT9425261E344
- Federal Grant Award Summary Sanford Burnham Prebys Medical Discovery Institute received a $195,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective August 1, 2025 through July 31, 2027. The research project, "Function and Therapeutic Potential of R Loops in Glioblastoma," will be conducted at the institute's La Jolla, California facility and is designed to advance fundamental and...
- Federal Project Grant Award Summary Sanford Burnham Prebys Medical Discovery Institute received a $1,078,882 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective May 1, 2025, through April 30, 2027. The award supports research applying chemical engineering approaches to amyotrophic lateral sclerosis (ALS) treatment, with a focus on advancing understanding of the multimodal therapeutic actions of donor and host neural...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded $1.4M under the Military Medical Research and Development program (CFDA 12.420) to The Regents of the University of California, San Francisco, effective July 1, 2026, through July 31, 2029. This project grant funds basic and applied biomedical research investigating the metabolic mechanisms of resistance to mutant isocitrate dehydrogenase (IDH) inhibition in gliomas. The research will be conducted at UCSF's San Francisco...
- Federal Project Grant Award Summary The Sloan-Kettering Institute for Cancer Research received a $176,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective November 1, 2025, through October 31, 2027. The award funds research exploring a novel antibody-drug conjugate (ADC) strategy designed to block MYC protein production in neuroblastoma (NB), a pediatric cancer of the nervous system. This research...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded $352,000 under the Military Medical Research and Development program (CFDA 12.420) to the Sloan-Kettering Institute for Cancer Research for the project period September 1, 2025, through August 31, 2027. The award supports research focused on augmenting the in vivo efficacy of a novel lanosterol synthase inhibitor in glioblastoma treatment. This research aligns with the DHA's mission to transform healthcare for service...
- This federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program provides $571,350.00 in funding to the Sanford Burnham Prebys Medical Discovery Institute (SBP) in La Jolla, California. The award supports research aimed at developing metabolic interventions to halt the progression of pancreatic cancer. SBP, an independent non-profit biomedical research organization, will leverage advanced technologies and...
- This $682,472 federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program supports research by the Sanford Burnham Prebys Medical Discovery Institute (SBP) to selectively target mutant SHP2 oncoproteins in rare leukemias. The award will fund SBP's efforts to advance understanding of the fundamental mechanisms of disease and develop innovative therapies, with a focus on areas such as cancer, aging, neurodegenerative...
- The Defense Health Agency awarded a $1,535,920.00 Project Grant to the Translational Genomics Research Institute (TGen) under the Military Medical Research and Development program (CFDA 12.420). The grant supports TGen's research on genomic structural mutations associated with telomere dysfunction in glioblastoma cells and patients. The 4-year project will utilize advanced genomic analysis and sequencing techniques to gain insights into the molecular mechanisms driving glioblastoma, a highly...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded Beckman Research Institute of the City of Hope a $1.4 million Project Grant on August 31, 2026, under the Military Medical Research and Development program (CFDA 12.420) to support research targeting aberrant end-joining repair for improving treatment of mixed phenotype acute leukemia. The three-year project, which extends through July 31, 2029, will be conducted at the Institute's research facility in Irwindale, California....
- Federal Project Grant Award Summary The University of California, San Francisco (UCSF) received a $328,000 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), effective July 1, 2025, through June 30, 2027. The award funds research on intracranial drug delivery strategies targeting skull bone marrow to generate antitumoral myeloid cell immune responses against glioblastoma. This research initiative represents UCSF's...
Sanford Burnham Prebys Medical Discovery Institute received a $140,000 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), with an award date of August 1, 2026, and an ultimate completion date of July 31, 2028. The research project, titled "Targeting Glioblastoma with a First-in-Class BRD8 Molecular Glue Degrader and Temozolomide," focuses on investigating novel therapeutic approaches for glioblastoma, a primary brain cancer. The project combines a first-in-class BRD8 (bromodomain-containing protein 8) molecular glue degrader compound with temozolomide, a standard chemotherapy agent, to advance preclinical and translational research applicable to Service Member health and the broader military population. The research will be conducted at the awardee's facility in La Jolla, California, over the two-year funding period. This award aligns with the DHA's portfolio of investigator-initiated biomedical research spanning cancer biology, neurodegeneration, and translational medicine addressing unmet medical needs. Sanford Burnham Prebys, a nonprofit biomedical research organization with substantial experience managing federal research grants, will deliver research findings, data, and scientific outputs supporting the development of innovative therapeutic strategies for glioblastoma treatment.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $140.0k | 7/16/26 |