Project Grant HT9425261E318
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded $7.999 million to the University of California, Los Angeles (UCLA) under the Military Medical Research and Development program (CFDA 12.420) on August 1, 2026, for a Phase 1 single-blind, placebo-controlled, dose escalation study evaluating the safety of AD-NP1, a humanized monoclonal antibody targeting human enpp1 (ectonucleotide pyrophosphatase/phosphodiesterase 1). The project, to be conducted at UCLA's Los Angeles...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded UCLA a $799,999 Project Grant effective May 1, 2026, through April 30, 2030, under the Military Medical Research and Development program (CFDA 12.420). The project, titled "From H & E to HRD: Linking Morphometry, Clinical, and Molecular Data for Drug Response Prediction," supports biomedical research designed to advance medical solutions for Service Members and the military population. This award represents...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded a $528,641 Project Grant to the University of California, Los Angeles (UCLA) effective July 1, 2026, through June 30, 2028, under the Military Medical Research and Development program (CFDA 12.420). The award supports investigator-initiated biomedical research focusing on extracellular vesicles as biomarkers in non-Hodgkin's lymphoma (NHL). This research aligns with the DHA's broader mission to advance medical solutions...
- Federal Project Grant Award Summary The Defense Health Agency (DHA), through its Military Medical Research and Development program (CFDA 12.420), awarded a $157,500 Project Grant to the University of California, Los Angeles (UCLA) Office of Research Administration, effective September 1, 2025, with completion scheduled for August 31, 2026. The award supports research investigating the impact of a hypomorphic SMARCB1 germline allele specific for schwannomatosis on mouse development and...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded the University of California, Los Angeles a $1.70 million Project Grant on June 1, 2026, under the Military Medical Research and Development program (CFDA 12.420) to conduct research on "The 3D Multiomic Determinants of Prostate Cancer Lethality." The three-year project, with completion targeted for May 31, 2029, will be performed at UCLA's Los Angeles campus and is expected to deliver investigator-initiated biomedical...
- Federal Project Grant Award Summary The Defense Health Agency awarded the University of California, Los Angeles a $1.5M Project Grant on July 1, 2026, through the Military Medical Research and Development program (CFDA 12.420) to develop a personalized and actionable brain health prediction algorithm for post-9/11 warriors. The four-year award, with completion scheduled for June 30, 2030, supports biomedical research addressing Service Member health outcomes and conditions affecting the military...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded UCLA a $2.16M Project Grant on September 30, 2025, under the Military Medical Research and Development program (CFDA 12.420) to conduct research on cerebellar neuromodulation to reduce cognitive dysfunction after multiple subconcussive impacts. The four-year project, scheduled for completion on September 29, 2029, will be performed at UCLA's Los Angeles campus through the Office of Research Administration. This award supports...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded a $2,076,089 Project Grant to the University of California, Los Angeles (UCLA) beginning September 1, 2026 and concluding August 31, 2030 under the Military Medical Research and Development program (CFDA 12.420). The project, titled "Defining an Error-Free DNA Repair Signature as a Predictive Marker for Lethal Prostate Cancer," supports basic and applied biomedical research conducted at UCLA's Los Angeles,...
- This federal Project Grant award, valued at $2,520,000.00, was issued by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The award supports advanced biomedical research initiatives focused on transforming healthcare for military service members and the broader public. The primary awardee, the University of California, Los Angeles (UCLA), will leverage its extensive facilities, diverse faculty expertise, and robust administrative capabilities...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded The Regents of the University of California, San Francisco a $1.4 million Project Grant under the Military Medical Research and Development program (CFDA 12.420) effective July 1, 2026, through July 31, 2029. The award supports investigator-initiated research into the metabolic mechanisms of resistance to mutant isocitrate dehydrogenase (IDH) inhibition in gliomas. This three-year research initiative will be conducted at...
The Defense Health Agency (DHA) awarded University of California, Los Angeles a $1.75 million Project Grant on September 1, 2026, under the Military Medical Research and Development program (CFDA 12.420) to support a three-year research initiative titled "Deconstructing AAV-Associated Liver Toxicity: Biomarkers and Immune Insights to Enable Safer Gene Therapies." The project, which will be performed in Los Angeles, California, and is scheduled for completion by August 31, 2029, focuses on conducting biomedical research to identify and characterize biomarkers and immune mechanisms associated with adeno-associated virus (AAV) liver toxicity. This research directly supports DHA's mission to advance innovative medical solutions and transform health care for Service Members by addressing safety concerns related to gene therapy applications. The research deliverables will contribute to the broader Military Medical Research and Development program portfolio, which supports basic, applied, and advanced biomedical research addressing Service Member health and battlefield medicine. By elucidating the mechanisms of AAV-associated liver toxicity and developing improved biomarkers, this project will generate scientific insights to enable safer and more effective gene therapy approaches, with potential applications for military populations and the broader U.S. public health sector.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.7m | 6/23/26 |