Project Grant HT9425261E286
- Federal Project Grant Award Summary Children's Hospital Los Angeles received a $598,500 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective August 1, 2025 through July 31, 2028. The award supports research to establish diagnostic cutoff thresholds for minimal residual intraocular disease in retinoblastoma through analysis of extracellular vesicles obtained from aqueous humor liquid biopsy. This research...
- Federal Grant Award Summary Children's Hospital Los Angeles received a $1.4 million Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2026, through August 31, 2029. The award funds research to develop CTSR-enhanced chimeric antigen receptor (CAR) T cells designed to overcome the immunosuppressive tumor microenvironment and improve immunotherapy outcomes for pediatric brain tumors. This three-year...
- Federal Grant Award Summary Children's Research Institute received a $777,659 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period August 1, 2025 through July 31, 2028. The award supports research titled "Use of ProResolution and Restorative Pharmacology Approaches for DMD Therapy," focusing on the development of innovative therapeutic interventions for Duchenne muscular dystrophy (DMD). The...
- Federal Project Grant Award Summary Children's Research Institute received a $405,341 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for the period August 1, 2025 through July 31, 2028. The award supports research utilizing pro-resolution and restorative pharmacology approaches for Duchenne muscular dystrophy (DMD) therapy development. This research initiative advances biomedical innovation in support of the Defense...
- Federal Grant Award Summary Children's Mercy Hospital received a $1.65 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded August 1, 2026, with a completion date of July 31, 2029. The award supports biomedical research conducted at the hospital's Kansas City, Missouri facility addressing Service Member health and military-relevant medical conditions. As a pediatric medical center with an established...
- Grant Award Summary Children's Hospital Los Angeles received a $972,555 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective July 1, 2025, through June 30, 2029. The award supports the establishment of a comprehensive registry for atypical teratoid rhabdoid tumor (AT/RT), a rare pediatric malignancy. This registry will serve as a centralized data repository to facilitate clinical research, improve understanding...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded Beckman Research Institute of the City of Hope a $1.4 million Project Grant on August 31, 2026, under the Military Medical Research and Development program (CFDA 12.420) to support research targeting aberrant end-joining repair for improving treatment of mixed phenotype acute leukemia. The three-year project, which extends through July 31, 2029, will be conducted at the Institute's research facility in Irwindale, California....
- Federal Grant Award Summary ST Jude Children's Research Hospital Inc. received a $560,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2026, with completion targeted for August 31, 2028. The project, titled "Direct Targeting of Oncohistone Mutations in Diffuse Midline Glioma," represents basic and applied biomedical research addressing pediatric cancer biology within the DHA's...
- Federal Grant Award Summary The Children's Hospital of Philadelphia Research Institute received a $676,117 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) beginning September 1, 2025, with completion scheduled for August 31, 2029. The research project focuses on expanded GAA-GGA chimeric repeats in Friedreich Ataxia, a rare neurological genetic disorder. This award supports biomedical research aimed at advancing medical...
- Federal Grant Award Summary The Defense Health Agency (DHA) awarded University of California, Los Angeles a $799,999 Project Grant on May 1, 2026, under the Military Medical Research and Development program (CFDA 12.420) to support the project "From H&E to HRD: Linking Morphometry, Clinical, and Molecular Data for Drug Response Prediction." The award, with an ultimate completion date of April 30, 2030, funds biomedical research aimed at integrating histopathological imaging...
Children's Hospital Los Angeles received a $1.012 million Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), awarded September 15, 2026, with performance through September 14, 2030. The award funds the development of an international multi-institutional aqueous humor biorepository designed to support biomarker research in rare ocular cancers. This initiative will establish a centralized biological specimen repository and associated data infrastructure to enable collaborative research across multiple institutions, facilitating the identification and validation of diagnostic and prognostic biomarkers in understudied ocular cancer populations relevant to military and public health interests. The Defense Health Agency funds this project as part of its broader portfolio supporting biomedical research addressing Service Member health and conditions affecting the military population. The biorepository will leverage Children's Hospital Los Angeles's existing infrastructure in biospecimen handling, clinical data collection, and multi-institutional collaboration—capabilities demonstrated through its participation in pediatric research consortia and clinical trial networks. The four-year project timeline aligns with standard Defense Health Agency award structures, which typically range from three to four years and support investigator-initiated research in rare diseases and specialized medical conditions.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 6/11/26 |