Project Grant HT9425261E085
- This federal Project Grant award of $704,431.23 from the Defense Health Agency (CFDA 12.420 - Military Medical Research and Development) to Meso Scale Diagnostics LLC, doing business as Meso Scale Discovery, supports the development of ultrasensitive plasma and cerebrospinal fluid immunoassays to enable clinical trials for amyotrophic lateral sclerosis (ALS). As a for-profit limited liability company specializing in assay development, laboratory testing, and related products for biomedical...
- Federal Grant Award Summary Wayfinder Biosciences Inc. received a $680,591 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to conduct research on a novel small molecule screening approach for direct and selective targeting of repeat expansion RNA in C9ORF72 Amyotrophic Lateral Sclerosis (ALS). The award, issued on June 15, 2025, with a completion date of December 14, 2026, funds hypothesis-driven biomedical research...
- Federal Project Grant Award Summary Award Details: Modulo Bio, Inc. received a $1.74M project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) with an award date of May 1, 2026, and a performance period through April 30, 2028. This administrative modification corrected the payment office DODAAC code for processing purposes without altering the award amount or other terms and conditions. Products and Services: Under this award,...
- Federal Project Grant Award Summary The University of Miami's Office of Research Administration - School of Medicine received a $999,999 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) on June 1, 2026. The award funds research titled "Schwann Cell-Derived Extracellular Vesicle Platform for ALS Biomarker Discovery in Biofluids" with a completion date of May 31, 2029. This project delivers biomarker discovery research...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded The Methodist Hospital Research Institute a $998,039 project grant under the Military Medical Research and Development program (CFDA 12.420) to conduct a large-scale multiomic study identifying systemic and central immune-related biomarkers in amyotrophic lateral sclerosis (ALS). The three-year research initiative, commencing May 1, 2026 and concluding April 30, 2029, will be performed at the institute's Houston, Texas...
- Federal Grant Award Summary New York University School of Medicine received a $1.0 million Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for the three-year period from June 1, 2026, through May 31, 2029. The award funds research into diffusion magnetic resonance imaging (MRI) biomarkers of axonal degeneration in amyotrophic lateral sclerosis (ALS). This research initiative will advance understanding of neurodegeneration...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded $939,325 to the Weizmann Institute of Science on November 1, 2025, under the Military Medical Research and Development program (CFDA 12.420) to support the GLOBALS (Global Omic Biomarker Research for ALS) initiative. This three-year project, extending through October 31, 2028, funds advanced biomedical research focused on discovering and developing omic biomarkers for amyotrophic lateral sclerosis (ALS). The research...
- This federal Project Grant award, valued at $1,103,084.00, was issued by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The funding supports the development of a personalized blood-based diagnostic assay for early detection of Amyotrophic Lateral Sclerosis (ALS) at Arizona State University. The university will collaborate with a sub-awardee, Georgetown University, to conduct the research. The project aims to transform healthcare for...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded $840,000 to Barrow Neurological Institute at St. Joseph's Hospital and Medical Center under the Military Medical Research and Development program (CFDA 12.420) for the project "Targeting M6A Dysregulation in ALS via Small Molecule Approaches." The award, effective July 1, 2026, through June 30, 2028, supports research and development activities focused on investigating therapeutic interventions for...
- This Project Grant award, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research to develop neuronal exosome-based biomarkers for the diagnosis and disease progression of amyotrophic lateral sclerosis (ALS). The total award amount is $1,181,251.00, with a performance period from April 15, 2025 to April 14, 2028. The principal investigator for this grant is the University of California, Los Angeles (UCLA), which has a...
Meso Scale Diagnostics LLC (doing business as Meso Scale Discovery) received a $997,807 project grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for the period July 1, 2026 through June 30, 2028. The award supports the development of ultrasensitive immunoassays for detecting TDP-43 pathology, a biomarker associated with neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). This research initiative leverages the awardee's core expertise in electrochemiluminescence-based detection platforms and advanced immunoassay development to create diagnostic tools that advance clinical trial capabilities and therapeutic research. The project aligns with the Defense Health Agency's strategic focus on neurodegenerative disease biomarker development and translational research. As a Native American-owned small business, Meso Scale Diagnostics brings specialized capabilities in multiplex assay development and biomarker discovery, with demonstrated experience supporting military health priorities and broader public health objectives. The ultrasensitive immunoassay development delivered through this award is expected to support ongoing ALS research initiatives and contribute to the advancement of precision diagnostic technologies for neurodegenerative conditions.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $997.8k | 4/7/26 |