Project Grant HT9425261E060
- Federal Grant Award Summary The Cleveland Clinic Foundation received a $700,000 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective May 1, 2026 through April 30, 2030. The award supports research investigating the role of the gut and tumor microbiome on ovarian cancer progression and resistance to chemotherapy. This research initiative aligns with the DHA's portfolio of hypothesis-driven biomedical research...
- Federal Grant Award Summary The Cleveland Clinic Foundation received a $750,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective April 1, 2026 through March 31, 2029. The project, titled "Leveraging Focal Adhesion Dependencies in CDH1-Deficient Lobular Breast Cancers," will be conducted at the organization's Cleveland, Ohio facility. This research initiative represents a hypothesis-driven...
- Federal Grant Award Summary The Cleveland Clinic Foundation received a $1.28 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2029. This four-year research award supports investigation of the biological mechanisms and therapeutic relevance of the SLC1A1 amino acid transporter in kidney cancer. The research will be conducted at the Cleveland Clinic Foundation's...
- Federal Project Grant Award Summary The Cleveland Clinic Foundation received a $559,992 project grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) awarded on September 30, 2025, with a completion date of September 29, 2028. The award supports bench-to-bedside development of superior CAR (Chimeric Antigen Receptor) T-cell therapy for leukemia, conducted at the organization's Cleveland, Ohio facility. This research initiative...
- This federal Project Grant award from the Department of Defense's Military Medical Research and Development program (CFDA 12.420) provides $1,159,998.00 to The Cleveland Clinic Foundation, a non-profit academic medical center, to fund a research project titled "THERAPEUTIC IMMUNOSTIMULATORY MICROBES FOR TREATMENT OF OVARIAN CANCER". The award, which runs from September 1, 2024 to August 31, 2028, will support the Foundation's innovative biomedical research into developing...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded The Cleveland Clinic Foundation a $999,566 project grant effective November 1, 2025, through October 31, 2028, under the Military Medical Research and Development program (CFDA 12.420). The award supports a three-year research initiative focused on magnetic resonance imaging-guided transcriptomic analysis of spinal cord neurodegeneration and demyelination in multiple sclerosis. This project represents a hypothesis-driven...
- This federal Project Grant award, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), is funding advanced biomedical research conducted by The Cleveland Clinic Foundation to investigate a novel mechanism for disrupting ovarian cancer progression. The total award amount is $780,357.00, with a performance period from May 1, 2025 to April 30, 2029. The research aims to elucidate the nuclear localization of the complement regulator CD55 as...
- The U.S. Department of Defense's Defense Health Agency (DHA) awarded a $2,602,024 Project Grant to The Cleveland Clinic Foundation under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant, awarded on September 30, 2024, will fund research on the "Role of Stress in the Degradation of Intestinal IgA and Intestinal Health" over a 4-year period ending on September 29, 2028. As a prominent academic medical center, The Cleveland Clinic Foundation...
- The Defense Health Agency awarded a $640,000 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The Cleveland Clinic Foundation, a non-profit academic medical center, to conduct research focused on "Evolutionary Experimentation Highlights Novel Therapeutic Vulnerabilities in Endometrial Cancer." The award duration is from September 1, 2024 to August 31, 2026. The Cleveland Clinic Foundation, which has extensive experience as both a prime...
- This Project Grant award of $471,000.00 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The funding supports research by The Cleveland Clinic Foundation to develop next-generation prostate cancer therapeutics by exploiting the allosteric regulation of the androgen receptor. The award period is from September 1, 2023 to August 31, 2025. As a prime recipient of federal grants, The Cleveland Clinic Foundation has a history of...
The Cleveland Clinic Foundation received a $700,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective May 1, 2026 through April 30, 2030. The award funds research to decipher the role of the gut and tumor microbiome on ovarian cancer progression and resistance to chemotherapy. This hypothesis-driven research initiative aligns with the DHA's mission to transform healthcare for military service members and the American public through innovative biomedical solutions addressing critical health challenges, with a specific focus on oncology research. The research will be conducted at Cleveland Clinic Health System's facilities in Cleveland, Ohio, leveraging the organization's established expertise in cancer immunotherapy and biomedical research. As a prominent academic medical center with a robust federal grant portfolio exceeding $20 million in prior DHA awards, Cleveland Clinic will deliver translational research and biomarker discovery services to advance understanding of microbiome-related mechanisms affecting ovarian cancer therapeutics and treatment outcomes.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $700.0k | 4/3/26 |