Project Grant HT94252510793

This Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) totals $257,116 and will be performed by Purdue University from September 1, 2024 to August 31, 2026. The award will fund a randomized, double-blind, sham-controlled clinical trial to determine the effects of daily home-based leg heat therapy on exercise capacity and quality of life in 34 older women with heart failure and preserved ejection...

This $1,322,854 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research to determine the safety, tolerability, and efficacy of home-based lower body heat therapy in late middle-age and older adults with post-acute sequelae of SARS-CoV-2 infection (PASC). The primary objectives are to assess whether lower body heat therapy can: 1) safely and effectively improve cognitive and physical function, 2) attenuate inflammation and improve vascular and...

This $1,473,664 Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will support research to examine the potential benefits of local heat therapy for improving skeletal muscle architecture, glycemic control, and physical function in older adults at risk for type 2 diabetes. The overall hypothesis is that local heat therapy can improve skeletal muscle characteristics, glucose tolerance, and frailty indicators, potentially providing an alternative to...

This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) is focused on testing the effectiveness and implementation of a home-based exercise intervention for individuals with an implantable cardioverter defibrillator (ICD). The primary goal is to determine if the Exercise-ICD (E-ICD) intervention can increase physical activity and improve related health outcomes in this patient population. The $728,781 award to the...

This federal Project Grant award of $211,988 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports research at The University of Texas Southwestern Medical Center to evaluate low-energy cooling strategies for mitigating the adverse health effects of heat waves on the elderly. The research aims to test the efficacy of skin wetting and fan use in attenuating increases in core body temperature and cardiovascular/renal...

The federal Project Grant award R34AT012767, provided by the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), will fund feasibility and acceptability testing of an integrated intervention combining digital cognitive behavioral therapy for insomnia (dCBT-I) and passive body heating (PBH) for the treatment of insomnia disorder. The $737,480 award will support two studies: (1) an iterative...

This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $1,970,848 to The Children's Hospital of Philadelphia to evaluate the efficacy of a digital intervention to increase physical activity and improve physical fitness in youth with the Fontan circulation. The study involves a randomized controlled trial with three specific aims: 1) Determine if the multi-component digital intervention increases physical activity...

This federal Project Grant award of $792,235 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development and execution of a randomized clinical trial to evaluate the effectiveness of a commercially available fitness mHealth app (Rehabbing with Peloton) for improving physical activity among individuals recovering from transcatheter aortic valve replacement (TAVR). The key products and services to be delivered under this grant include:...

This federal Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) is providing $940,798 to The Miriam Hospital to develop an optimized, stepped care intervention to help under-resourced patients maintain improvements in key health behaviors after completing cardiac rehabilitation. The project will utilize a sequential, multiple assignment, randomized trial (SMART) design to create an adaptive intervention that minimizes patient burden....

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $613,744 to Assistive Technology Development Inc. to develop a lightweight, cost-effective robotic telerehabilitation device for patients with musculoskeletal conditions. The device will provide motorized exercise modes coupled with blood flow restriction to enhance the...