Polygenicity of brain and physical reserve in multiple sclerosis

The University of Manitoba received a $249,823 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025 through August 31, 2027. The research project, titled "Polygenicity of Brain and Physical Reserve in Multiple Sclerosis," will be conducted at the university's facility in Ottawa, Ontario, Canada. This award supports hypothesis-driven biomedical research aimed at advancing understanding of multiple sclerosis (MS) through investigation of genetic and physiological factors that contribute to brain and physical reserve mechanisms in affected individuals.

As a recognized research institution with extensive experience in neuroscience and medical research, the University of Manitoba will deliver advanced scientific research outputs including data analysis, research findings, and scholarly publications derived from the two-year study period. The research aligns with the Military Medical Research and Development program's focus on investigating medical solutions for conditions relevant to military service members and the broader public, with particular emphasis on neurological disorders. Awards under this program are designed to support research ranging from basic scientific investigation through advanced clinical applications, with findings expected to contribute to improved healthcare outcomes for affected populations.