APOBEC3, a HIT-and-run driver responsible for breast cancer initiation and/or progression?

This $695,251 federal Project Grant award from the Department of the Army Medical Command's Military Medical Research and Development program (CFDA 12.420) supports advanced biomedical research by The Hospital for Sick Children (Sick Kids Hospital) in Toronto, Canada. The grant funds a study investigating the potential role of the APOBEC3 protein in breast cancer initiation and/or progression. Sick Kids Hospital, a leading pediatric research institution, will contribute its scientific expertise, research infrastructure, and clinical capabilities to this 3-year research initiative, which commenced on August 1, 2024 and is scheduled for completion by July 31, 2027. The award leverages Sick Kids' extensive experience serving as both a prime recipient and subcontractor on numerous prior federal grants and contracts, including work with partners like the University of Alabama at Birmingham, Oregon Health & Science University, and the University of Wisconsin System.