Project Grant HT94252410741

This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $1,623,261 to Case Western Reserve University to conduct a clinical trial and develop novel molecular technologies for early detection and prevention of esophageal adenocarcinoma. Specifically, the project aims to: 1) demonstrate the efficacy of a non-endoscopic, biomarker-based approach to detect Barrett's esophagus, a precursor to esophageal cancer, in a population...

The National Cancer Institute (NCI), under the Cancer Cause and Prevention Research Federal Grant Program (CFDA 93.393), awarded a $323,226 Cooperative Agreement to the Regents of the University of Michigan to fund a project titled "Developing Natural Products to Target IL-8 Signaling and Intercept Progression of Barrett's Esophagus to Esophageal Adenocarcinoma." The project, running from August 1, 2025 to July 31, 2028, aims to conduct comprehensive research to understand, prevent,...

This Project Grant awarded by the National Cancer Institute (NCI), under the federal Cancer Detection and Diagnosis Research program (CFDA 93.394), provides $399,789 to Ergami Endoscopy, Inc. to develop an automated robotic flexible overtube device capable of blind insertion during colonoscopy procedures. The device aims to reduce physician injuries, improve productivity, and decrease patient pain/sedation requirements for the over 16 million colonoscopies performed annually in the U.S. Key...

This $656,000 federal Project Grant award, made on May 15, 2025 by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports advanced biomedical research at the University of California, San Francisco (UCSF) to investigate the role of myeloid cells and other inflammatory components in the progression of Barrett's esophagus to invasive esophageal adenocarcinoma. The project will be conducted over a 2-year period through May 14, 2027. As a...

The Vermont Colorectal Cancer (CRC) Screening Program, funded through a $449,702 Cooperative Agreement from the Centers for Disease Control and Prevention's (CDC) Organized Approaches to Increase Colorectal Cancer Screening program (CFDA 93.800), aims to increase CRC screening rates among adults aged 45 to 75 in Vermont. The program will collaborate with three Federally Qualified Health Centers (FQHCs) and one community health center to implement evidence-based interventions designed to boost...

This federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) to the Sloan-Kettering Institute for Cancer Research provides $263,086 to develop a multiparametric endoscopic ultrasound (MPEUS) imaging system and methodology for improved pancreatic cancer screening and characterization. The goal is to create a non-subjective, quantitative approach for detecting and characterizing pancreatic cancer and precursor lesions in high-risk...

This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $813,000 to Safeguard Surgical, Inc. to develop and evaluate a biodegradable barrier device called LeakGuard that can prevent anastomotic leaks in patients undergoing esophagectomy surgery. The key objectives of this SBIR Phase I project are to: 1) assess the mechanical and degradation properties of LeakGuard under esophageal-like conditions, and 2) demonstrate LeakGuard's ability to...

The Commonwealth of Virginia-State Board of Health, through its Richmond City Health District division, has been awarded a $683,891 cooperative agreement from the Centers for Disease Control and Prevention (CDC) under the "Organized Approaches to Increase Colorectal Cancer Screening" (CFDA 93.800) program. This 5-year award, effective August 30, 2025, aims to improve colorectal cancer screening rates among Virginia residents aged 45-75, particularly those served by Federally...

The Centers for Disease Control and Prevention (CDC) awarded a $532,805 Cooperative Agreement under the "Organized Approaches to Increase Colorectal Cancer Screening" program (CFDA 93.800) to the Health Services Kentucky Cabinet For to implement evidence-based interventions and strategies to increase colorectal cancer (CRC) screening rates in partnered health systems serving Kentucky communities with limited CRC screening resources, particularly in rural areas of Western and Eastern...

This is a Cooperative Agreement award from the Centers for Disease Control and Prevention (CDC) under the Organized Approaches to Increase Colorectal Cancer Screening program (CFDA 93.800). The award of $532,090 to Louisiana State University Health Sciences Center New Orleans will fund the Louisiana Colorectal Health Project, known as "Screen Up." The project aims to increase colorectal cancer (CRC) screening rates in Louisiana by partnering with health systems to implement...