Project Grant HT94252410667

The Department of the Army Medical Command awarded a $5.95 million cooperative agreement to The Johns Hopkins University on September 30, 2022 under the Military Medical Research and Development program (CFDA 12.420). The four-year award will fund a randomized controlled trial to evaluate cognitive-behavioral therapy versus mindfulness-based treatment for insomnia and post-traumatic stress symptoms related to traumatic brain injury. Sub-awards were provided to The Henry M. Jackson Foundation For...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $423,624 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Rutgers, The State University to conduct research on sleep and circadian rhythm disorders following traumatic brain injury (TBI). The project aims to use the Drosophila melanogaster genetic model to 1) identify genes that contribute to TBI-induced changes in sleep and circadian rhythms, and...

The U.S. National Institute on Aging (NIA) awarded a $134,000 project grant under the Aging Research program (CFDA 93.866) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct a pilot study on a digital cognitive behavioral therapy for insomnia (DCBT-I) intervention for older adults undergoing orthopedic surgery. The goal is to evaluate the feasibility and efficacy of this abbreviated DCBT-I protocol in improving sleep and cognitive resilience...

The federal Project Grant award R21HD117284 was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $346,500 award supports a randomized clinical trial to evaluate the efficacy of a multidimensional sleep health intervention in improving concussion recovery outcomes among adolescents. The intervention, delivered through the University of Colorado-Denver, addresses factors such...

This federal Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), will provide $689,449 to support a proof-of-concept feasibility study on an app-based mindfulness meditation intervention for patients with chronic insomnia disorder. The key objectives are to: (1) refine the content delivery of the app-based mindfulness meditation intervention, specifically...

This $808,417 federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports a study to evaluate the role of the metabotropic glutamate receptor subtype 5 (mGluR5) in the antidepressant mechanism of cognitive behavioral therapy for insomnia (CBT-I) in adults with major depressive disorder. The key objectives are to (1) determine if CBT-I reduces mGluR5 density, (2) correlate mGluR5 density reductions with...

The federal Project Grant award R34AT012767, provided by the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), will fund feasibility and acceptability testing of an integrated intervention combining digital cognitive behavioral therapy for insomnia (dCBT-I) and passive body heating (PBH) for the treatment of insomnia disorder. The $737,480 award will support two studies: (1) an iterative...

The Department of the Army Medical Command awarded a $2,430,944 project grant under the Military Medical Research and Development program (CFDA 12.420) to the University of Texas Health Science Center of San Antonio. The grant aims to develop a web-based training for cognitive behavioral therapy for nightmares (CBT-N) to be delivered from September 1, 2021 through August 31, 2025. Several sub-awards were provided to partner organizations to support content development, video production,...

This $7.72 million project grant from the National Institute on Aging, part of the Department of Health and Human Services, supports research under the Aging Research program (CFDA 93.866). The Seattle Institute for Biomedical and Clinical Research will define the role of post-traumatic brain injury sleep disruption and glymphatic dysfunction in the development of Alzheimer's disease and chronic traumatic encephalopathy neuropathology. Over three years, the grantee and three sub-awardees will...

This Project Grant awarded by the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) provides $2,218,222.00 to conduct a randomized clinical trial evaluating the efficacy of brain games and transcranial electrical stimulation in improving cognitive and functional outcomes for active duty service members and veterans with mild traumatic brain injury. The key products/services to be delivered include a four-arm Phase 2 clinical trial...