This federal Project Grant award, valued at $3,618,191.00 and issued on July 1, 2024, is funded by the Defense Health Agency through the Military Medical Research and Development program (CFDA 12.420). The award supports the development of a portable hemodialysis device to facilitate home use and field implementation.
The primary awardee, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., will lead the research and development efforts. This includes optimizing a titanium dioxide-based catalysis system for photo-oxidation of urea, assessing the utility of activated charcoal and other adsorptive agents for mitigating oxidative byproducts and removing additional uremic toxins, and building a mathematical kinetic model to account for dialytic uremic toxin removal and adsorption. The University of Washington is a key sub-awardee, providing technical expertise and support for the catalyst development and device design optimization.
The overall objective of this award is to advance portable hemodialysis technologies that can be effectively used in both home and field settings, ultimately improving healthcare delivery and outcomes for military service members and the broader patient population.