Understanding gene X stress interactions across the cell types of the brain in ptsd

Active Project Grant Awarded Last action

Award ID
HT94252311068
Recipient
Awarding agency
Obligated
$5,596,529

Award facts

Assistance listing
12.420 Military Medical Research and Development
Completion date 78% complete
Place of performance
New York, NY 10029, USA

Award details come from USAspending.gov.

About this award

The U.S. Department of Defense's Military Medical Research and Development program (CFDA 12.420) has awarded a $5,596,529 project grant to the Icahn School of Medicine at Mount Sinai to conduct research on understanding the interactions between gene X and stress across different brain cell types in post-traumatic stress disorder (PTSD). This 4-year grant, awarded on Sep 30, 2023, will fund studies to establish a human induced pluripotent stem cell-based platform for testing the functional impact of PTSD genetic variants. Sub-awards have been made to Yale University and the New York Stem Cell Foundation to provide expertise in functional genomics, stem cell derivation and differentiation, and high-throughput imaging assays to support this collaborative research effort aimed at uncovering new insights into PTSD pathogenesis.

Subawards

Subrecipient Amount Awarded
Jackson Laboratory The JAX-NYSCF Collaborative (NYSCF), under the direction of Co-PI Daniel Paull, Ph.D., will derive and reprogram fibroblast samples from collaborators at the… $693,881
Yale Univ The Brennand and Huckins Labs of the Yale School of Medicine will apply functional genomic methods to establish a robust hiPSC-based platform for testing the… $991,042
New York Stem Cell Foundation Inc. The NYSCF Research Institute, under the direction of Co-PI Daniel Paull, Ph.D., will derive and reprogram fibroblast samples from collaborators at the Mount… $895,608

Quick answers

Who received award HT94252311068?

HT94252311068 was awarded to Icahn School Of Medicine At Mount Sinai by Defense Health Agency (Department of Defense) on September 30, 2023.

How much is award HT94252311068 worth?

$5,596,529 has been obligated on HT94252311068.

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