This Project Grant award from the Defense Health Agency under the Military Medical Research and Development Program (CFDA 12.420) provides $2,495,419.00 to The Trustees of the University of Pennsylvania (Penn) to develop a blood-based biomarker for detecting blood-brain barrier dysfunction in traumatic brain injury. The project aims to transform healthcare for service members and the public by developing innovative medical solutions for the battlefield through July 1, 2023 to June 30, 2027....
The U.S. Department of Defense's Military Medical Research and Development program (CFDA 12.420) awarded a $683,442 Project Grant on September 1, 2023 to The Trustees of the University of Pennsylvania to conduct a 3-year study on "Trajectories of Neuroimaging and Blood-Based Biomarkers After Remote Traumatic Brain Injury and Associations with Dementia Risk." The University of Pennsylvania will collaborate with Mayo Clinic on a sub-award to investigate longitudinal changes in brain...
This federal Project Grant award, valued at $3,102,638.00 and spanning August 15, 2024 to July 31, 2027, was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to The Trustees of the University of Pennsylvania. The grant aims to develop novel gyrencephalic animal models that can recapitulate the complex neuropathological and clinical features associated with traumatic brain injury (TBI)-induced Alzheimer's disease and related dementias (ADRD). The project will evaluate...
The federal Project Grant award, valued at $2,699,157.00 and effective from July 1, 2025 to June 30, 2029, is funded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The grant supports research to assess the effectiveness of a traumatic brain injury whole blood test in improving assessment and triage for patients with mild traumatic brain injury presenting to civilian emergency departments. The University of Pittsburgh, a renowned public...
This $6,699,872.00 Project Grant award from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports the "MICROGLIAL BREAKTHROUGHS IN LONGEVITY, AGING, AND SENESCENCE AFTER TBI (MICROBLAST)" research initiative at the University of Pittsburgh. The 4-year award, starting on Sep 30, 2024, aims to conduct advanced biomedical research focused on transforming healthcare for military service members, veterans, and the broader public by...
The federal Project Grant award of $777,537 was granted by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The award supports research to investigate associations between blood-based neurodegenerative biomarker trajectories and the risk of epilepsy, post-traumatic epilepsy, and dementia. This 3-year research project,...
This federal Project Grant award in the amount of $747,507 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant supports an evaluation of an engineered calpain activity nanosensor in a mouse model of traumatic brain injury (TBI) at the University of California, San Diego (UCSD). The objective of the research is to advance the development of innovative technologies for monitoring and assessing traumatic brain injuries,...
The University of Pittsburgh was awarded a $569,851 Project Grant by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The grant, effective from July 1, 2025 to June 30, 2029, will support research to assess the effectiveness of a traumatic brain injury whole blood test in improving the evaluation and triage of patients with mild traumatic brain injury presenting to civilian emergency departments. The Military Medical Research and Development...
This $309,279 Project Grant award, funded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports a research study on traumatic brain injury (TBI) and psychological health conducted by Florida State University. The primary objectives are to adapt the Ohio State University TBI Identification Method and the STAIR-NT intervention for first responders with TBI, analyze the data, and disseminate the study findings. Key sub-award activities...
This $6,214,900 Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program supports research on the role of genetic risk factors and immune response on neurovascular unit (NVU) function in post-traumatic brain injury (TBI) cognitive impairment. The primary awardee, the Scintillon Institute, a non-profit biomedical research organization in San Diego, California, will conduct this advanced scientific investigation over...