Project Grant HT94252310955

This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to develop an endovascular prosthetic graft device that can reduce common complications such as infection, neointimal proliferation, and thrombosis. The $311,824 award to Nytricx, Inc. will fund the integration of a nitric oxide (NO)-releasing polymer coating technology into the graft material to provide long-term regulation of these cellular processes at the...

This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Auxilium Health, Inc. to develop and validate an aerogel-based biomaterial wound dressing. The proposed dressing aims to promote tissue regeneration, block microbial infiltration, absorb wound fluid, and provide rapid visual indication of infection. The project seeks to optimize the aerogel's pore structure for biofilm...

This $655,533 Project Grant award from the Department of Defense's Military Medical Research and Development program (CFDA 12.420) supports research on the use of inhaled nitric oxide to treat microvascular dysfunction in traumatic brain injury. The principal grantee, The Trustees of the University of Pennsylvania, will conduct this 3-year research project in Philadelphia, Pennsylvania. Key activities include training staff on data acquisition using a diffuse optical neurometabolic monitor,...

This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering, under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, is focused on validating the performance and acceptability of a novel adhesive acrylic negative pressure wound therapy (NPWT) drape developed by Global Biomedical Technologies LLC. The $2,433,408 award will fund two randomized controlled trials to compare the performance of...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $300,000 in funding to Ionic Pharmaceuticals, LLC to develop a quorum sensing inhibitor-based treatment for second-degree burn wound infections caused by methicillin-resistant Staphylococcus aureus (MRSA). The key products or services to be delivered through this award include: 1) Optimizing the formulation of a...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) award of $305,000 to Therapeutic Bandage Products, Inc. will develop an advanced wound care product to rapidly heal diabetic foot ulcers. The patented microneedle bandage will deliver three therapeutic agents to disinfect the wound, prevent bacterial biofilm formation, and activate the immune system to clean up any residual infection. Initial work...

This $100,000 National Science Foundation Technology, Innovation, and Partnerships grant funds the development of tunable porosity aerogel for wound care dressings at The University of Akron from July 1, 2022 to June 30, 2023. The project aims to create a novel bio-based aerogel dressing that could help heal patients with chronic wounds faster by requiring fewer dressing changes. Aerogels' high porosity, surface area and moisture balance properties may create an incubator-like wound healing...

Emergency Medical Innovation LLC received a $256,000 Project Grant award from the National Science Foundation to develop a nasal compression device with medicated intranasal sponges for treating nosebleeds. Funded through the NSF's Engineering program (CFDA 47.041), the award will support design and testing of a nasal clip capable of consistently applying proper pressure levels and eluting appropriate doses of medication for nosebleed treatment when placed nominally. Over the one-year period...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $300,000 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) program to Singleto2 Therapeutics LLC, located in Summit, New Jersey. The project aims to develop and validate the efficacy of a superhydrophobic antimicrobial photodynamic therapy (SH-APDT) bandage for the prevention of multidrug-resistant burn wound infections. The SH-APDT bandage is designed to deliver airborne singlet oxygen,...