The objective for the proposed work is to develop methods to facilitate the quick identification of natural products in extracts and the quick identification of human protein targets

Active Project Grant Awarded Last action

Award ID
HDTRA12510013
Recipient
Awarding agency
Obligated
$963,360

Award facts

Completion date 30% complete
Funding agency
Defense Threat Reduction Agency Department of Defense
Place of performance
585 Av. Franklin Delano Roosevelt Ste 202, San Juan, 00936, Puerto Rico

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Omics technologies we should be able (1) to establish the chemical taxonomy of active compounds in a natural product mixture using high-resolution mass spectrometry with molecular networking and (2) to identify the human protein targets within the mixture using a human proteome array chip made by puerto rico-based company CDI laboratories. The proposal addresses a current GAP within the assigned thrust area 7 through expansion of the resources and capabilities available for drug discovery and development pipelines, as well as medical countermeasure development platforms. The technical approach for this project is an innovative one, which involves developing methods to facilitate the quick identification of natural products in extracts and the quick identification of human protein targets.

Transactions

Action Obligated Date
Amendment $0
Amendment Grant modification to add incremental funding to clin 0001. $481,680
Original award $481,680

Subawards

Subrecipient Amount Awarded
University Of Puerto Rico Mayagüez Campus will undertake following tasks: 1. Hire graduate student assistants to oversee the tasks associated with sample harvesting and collection. 2.… $28,926
University Of Puerto Rico This proposal is an ambitious project to identify natural toxins as well as their protein targets. The portion of the work dealing with the analysis of the… $38,926

Quick answers

Who received award HDTRA12510013?

HDTRA12510013 was awarded to Puerto Rico Science, Technology, And Research Trust by Defense Contract Management Agency (Department of Defense) on May 1, 2025.

How much is award HDTRA12510013 worth?

$963,360 has been obligated on HDTRA12510013.

Which agency awarded HDTRA12510013?

Defense Contract Management Agency (Department of Defense) awarded HDTRA12510013, with funding from Defense Threat Reduction Agency (Department of Defense).

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