Project Grant HDTRA12310001

This National Science Foundation project grant of $300,000 will fund research at the University of California, Los Angeles to develop scalable Bayesian dimension reduction methods for analyzing massive, dynamic network data related to global viral epidemics. Specifically, the award will support extending Bayesian multidimensional scaling to enable analysis of network data involving millions of observations. Theoretical and methodological work will develop a sparse coupling model and efficient...

This $711,555 federal Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to develop highly interpretable and predictive modeling frameworks for understanding the spatiotemporal transmission dynamics and control of vaccine-preventable childhood infections. The key objectives are to: 1) Integrate graph neural networks with compartmental models to create a flexible,...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3,275,000 Cooperative Agreement (CFDA 93.855 - Allergy and Infectious Diseases Research) to The Pennsylvania State University to implement an "Integrated Platform for Multiomic Analyses of Pathogen and Host Data Using Scalable Public Infrastructure." The project aims to establish a common data analysis workspace that will connect infectious disease researchers to data, tools, and workflows, providing access to...

The National Science Foundation awarded a $1,646,031 project grant under the Biological Sciences program (CFDA 47.074) to the University of Chicago for research titled "Combining Models and Data to Understand the Spatial Dynamics of Host-Pathogen Interactions." The grant period is from July 1, 2021 to June 30, 2025. The University of Chicago will lead research using mathematical models and data analysis to understand spatial dynamics between hosts and pathogens. Subawards were provided...

This $2,817,044 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports a comprehensive research program to investigate the complex host-pathogen interactions that influence tuberculosis (TB) infection outcomes. The program leverages novel mouse genetic resources and large panels of Mycobacterium tuberculosis (MTB) strains to study how the combinatorial complexity of host and bacterial diversity...

This federal Project Grant award of $793,247 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will fund research at the University of North Carolina at Chapel Hill (UNC-CH) to improve the health of people living with HIV. The key objectives of the research project are to: 1) develop and implement a data-driven algorithm to assign validated causes of hospitalizations among people with HIV, and use...

This $199,979 EAGER award from the National Science Foundation's Biological Sciences (CFDA 47.074) program will develop an open-source large language model to rapidly identify, verify, prioritize, summarize, and predict outcomes of emerging disease threats across humans, animals, and plants. The project, titled "The BioThreats Emergence, Analysis, and Communications Network (BEACON)", aims to create a specialized AI/machine learning system that can process vast datasets to detect...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $197,748.00 to The Regents of the University of California, San Francisco (UCSF) for a research project titled "Metagenomic Surveillance of Pathogen and Antimicrobial Resistance Gene Transmission in Hospitalized Neonates." The key objectives of this 5-year research project are to: 1) Identify nosocomial...

This federal Project Grant award of $237,136.00, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to map the virus-host interactions that determine interferon resistance of Seoul orthohantavirus. The research aims to identify the specific mechanisms by which the virus evades the host's innate immune response, particularly in reservoir rodent hosts versus human cells, in order...

This $133,182 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports the development of new point-process algorithms for modeling infectious disease threats over varying temporal and spatial scales. Specifically, the funding will be used to derive expectation maximization algorithms to infer probabilistic transmission networks for contact tracing and outbreak source detection. Multivariate Hawkes processes will be formulated to...