Project Grant F31CA301912
- Federal Project Grant Award Summary Award Overview Rockefeller University received a $100,228 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), awarded December 1, 2026, with a completion date of June 30, 2029. The award supports basic cancer research focused on identifying genes that fuel RAS-driven squamous cell carcinomas (SCCs), specifically investigating the genetic and environmental factors that enable cancer stem cells...
- Federal Grant Award Summary Rockefeller University received a $559,596 Project Grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396), effective July 1, 2026 through June 30, 2031. The award supports research to identify limiting mitochondrial metabolites that drive the initiation and progression of primary liver cancers, particularly hepatocellular carcinoma (HCC). The research leverages a proprietary organelle immunopurification technique...
- Federal Project Grant Award Summary The National Cancer Institute (NCI), under the Cancer Research Manpower program (CFDA 93.398), awarded the Regents of the University of Michigan $152,586 on December 12, 2025, for cancer research training and workforce development. The award, with a completion date of June 16, 2028, supports biomedical training opportunities designed to prepare individuals for careers in cancer research aligned with the National Cancer Program. The project, titled "MS4A...
- Federal Project Grant Award Summary New York University School of Medicine received a $149,190 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398) awarded December 1, 2025, with completion targeted for May 6, 2027. The grant supports biomedical research training and investigative work focused on elucidating the mechanisms of DNA methylation and its regulation by epigenetic histone modifications, with particular emphasis on understanding...
- This federal Project Grant award of $678,000.00 was issued on July 1, 2024 by the Defense Health Agency, under the CFDA 12.420 Military Medical Research and Development program, to Rockefeller University. The funding supports a 2-year research project titled "Finding Therapeutic Vulnerabilities in an AYA Cancer with CRISPR/Cas9". The project aims to conduct innovative biomedical research focused on improving health outcomes for military service members, veterans, and the broader...
- Federal Project Grant Award Summary Rockefeller University received a $1.65 million Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective August 1, 2026, through July 31, 2029. The award supports investigator-initiated research focused on therapeutic targeting of a commonly inherited breast cancer metastasis driver gene. This three-year project will deliver basic and applied biomedical research outcomes...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded $323,860 to Sloan-Kettering Institute for Cancer Research on August 18, 2025, under the Cancer Research Manpower program (CFDA 93.398) to support research investigating the role of mutagenic DNA repair during cancer cell persistence. The research will examine how cancer cells under stress from anti-cancer drug exposure shift their reliance from error-free DNA repair pathways—such as homologous recombination (HR)—to...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded MD Anderson Cancer Center $112,806 through the Cancer Research Manpower program (CFDA 93.398) on December 1, 2025, to support biomedical training and workforce development in cancer research. The award, which extends through April 30, 2028, funds a research training initiative investigating the role of CARM1-mediated methylation of QKI (quaking) protein in glioblastoma stem cell maintenance and tumor development. The project...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a Project Grant of $375,150 to The Regents of the University of California, San Francisco under the Cancer Treatment Research program (CFDA 93.395) to fund a five-year research initiative (September 1, 2025 – August 31, 2030). The research addresses innate resistance mechanisms to KRAS inhibitors in cancer treatment, focusing on the role of the RhoA-ROCK-Myosin IIA cytoskeletal axis in promoting drug-tolerant persister...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the University of Maryland, Baltimore a $2.84M Project Grant under the Cancer Treatment Research program (CFDA 93.395) to develop and evaluate improved cancer treatment methodologies. The award, effective August 18, 2025 through July 30, 2029, funds research focused on enhancing the therapeutic efficacy of cyclophosphamide (CPA) and doxorubicin (DOX)-based chemotherapy regimens while minimizing treatment-related toxicity....
Rockefeller University received a $100,228 Project Grant award from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), effective December 1, 2026 through May 31, 2028. The award supports research and training focused on characterizing Multidrug Resistance Protein 1 (MRP1) and developing MRP1-specific inhibitors to overcome chemoresistance in cancer treatment. The project addresses a critical clinical challenge, as drug resistance accounts for approximately 90% of treatment failures in metastatic cancer patients. The research aims to characterize MRP1 in native cell environments and design protein-based inhibitors targeting the extracellular region of MRP1, with the goal of preventing multidrug resistance while minimizing off-target toxicity that has plagued previous clinical candidates. This Cancer Research Manpower program grant supports biomedical training and workforce development in basic cancer research aligned with the National Cancer Program priorities. The award enables Rockefeller University to provide structured research training opportunities in molecular mechanisms and pharmacological approaches to addressing multidrug resistance, a key barrier to effective cancer therapy. By developing MRP1-selective inhibitors without cross-reactivity to other members of the multidrug resistance-associated protein family, the funded research has potential to enable novel cancer treatment strategies with improved tolerability profiles for patients experiencing chemoresistance.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 5/14/26 | ||
| Not listed | $50.1k | 5/14/26 | ||
| Not listed | $50.1k | 5/14/26 |