The impact of hearing and vestibular problems on physical function, psychosocial well-being, and survival outcomes among breast cancer survivors

Active Project Grant Awarded Last action

Award ID
F31CA301846
Recipient
Awarding agency
Obligated
$92,946

Award facts

Assistance listing
93.398 Cancer Research Manpower
Completion date 0% complete
Place of performance
Chicago, IL 60637, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer-related mortality among women in the united states. Due to improved survival and the growing aging population, the number of breast cancer survivors has increased, with ~4 million living with breast cancer in 2022. Breast cancer diagnosis and treatment can take a heavy toll on the physical, psychosocial, and financial health of patients, survivors, and their caregivers. Chemotherapy and radiotherapy are widely used to treat breast tumors, with neurosensory consequences. Aging is a significant risk factor for neurosensory dysfunction. Recent literature has suggested a 34-57% prevalence of hearing loss and a 30-60% prevalence of tinnitus among adult cancer survivors who underwent chemotherapy or radiation therapy. Hearing and vestibular problems, such as tinnitus or ringing in the ears, hearing loss, and vertigo or persistent dizziness, are prevalent among older adults and cancer survivors and represent emerging public health concerns in the united states. However, the relationships between hearing and vestibular problems and health outcomes and quality of life specifically among breast cancer patients and survivors are largely unknown. Previous studies are qualitative and descriptive. Additionally, most studies are comprised of mixed cancer types and/or less heterogeneous patient populations, precluding generalizability. Whether hearing loss and vestibular problems are associated with reduced physical function in breast cancer survivors is unclear as is how these conditions affect psychosocial well-being over time and mortality risks of these survivors. The proposed study will address these knowledge gaps by assessing hearing and vestibular problems and their associations with levels of physical function impairment, changes in psychosocial well-being, breast cancer-specific mortality, and all-cause mortality among breast cancer survivors enrolled in the chicago multiethnic epidemiologic breast cancer cohort study. This project will be the largest to date evaluating the relationships between hearing and vestibular problems and physical functioning. IT will also be the first to determine their impact on psychosocial well-being over time and the survival of breast cancer survivors. Study findings could help inform the practice of routine screening and early treatment or intervention for hearing and vestibular problems, increase awareness of and patient-provider discussion on these problems, and improve breast cancer survivors' health outcomes and quality of life. The study findings could also provide insight into neurosensory research in survivors of other cancers.

Transactions

Action Obligated Date
Amendment $46,473
Amendment $0
Original award $46,473

Quick answers

Who received award F31CA301846?

F31CA301846 was awarded to The University Of Chicago by National Cancer Institute (National Institutes of Health) on December 1, 2026.

How much is award F31CA301846 worth?

$92,946 has been obligated on F31CA301846.

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