Project Grant DESC0024850

The Biosyntheticmachines.com Inc. was awarded a $249,995 Project Grant from the Department of Energy Office of Science on February 21, 2023 to develop a computer environment supporting biosystem design guided by machine learning. The grant was awarded under the Office of Science Financial Assistance Program (CFDA 81.049), which supports scientific discoveries and tools to transform understanding of nature and advance U.S. energy and economic security. Specifically, this award will fund the...

The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $400,000 Project Grant to the Regents of the University of California at Riverside under the Engineering (47.041) federal grant program. The three-year award will support collaborative research using machine learning and synthetic biology approaches to engineer the thermotolerant yeast Kluyveromyces marxianus to maximize production of malonyl-coA, a key precursor to polyketides....

Geometric Data Analytics Inc. received a $249,252 Project Grant award from the Department of Energy Office of Science on February 14, 2022 to develop cloud-based biological data preparation, tracking, and checking technologies for artificial intelligence applications. The grant was awarded under the Office of Science Financial Assistance Program (CFDA #81.049), which supports basic research to deliver scientific discoveries and tools that transform understanding of nature and advance U.S. energy...

This Project Grant award of $592,981 from the National Science Foundation's (NSF) Geosciences Program (CFDA 47.050) will support collaborative research at the University of California, Santa Cruz (UCSC) to develop advanced machine learning models for analyzing flow cytometry data and mapping the geographic distribution of ocean microbes. The project aims to combine large datasets of flow cytometry measurements with novel neural network models to reveal patterns in the geographical distribution...

This Project Grant award of $350,000.00 from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of a new method for real-time measurement of endogenous biomolecules in live cells. The "TOOLS4CELLS" project at Tufts University aims to create a novel "turn-on biosensor" technology that can quantify changes in protein levels, such as beta-catenin, with much higher sensitivity and less background noise than existing methods. The...

Omicscraft LLC received a $256,000 Project Grant from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041) to develop a cloud-based platform for analysis of untargeted metabolomics data. The platform will provide users an interactive modular interface to build customized pipelines for metabolomics data analysis from February 15, 2022 through July 31, 2022. Key deliverables include innovative computational methods for...

This $741,002 federal Project Grant award from the National Science Foundation's Biological Sciences program supports the development of a novel machine learning framework for analyzing large-scale, multi-modal single-cell biological data. The project aims to construct advanced computational tools and user-friendly software to enable more effective extraction of insights and knowledge from complex single-cell datasets spanning genomics, transcriptomics, epigenomics, and proteomics. The...

This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) provides $369,297 to San Francisco State University (SFSU) to develop a synthetic transhydrogenation module to enhance the production of valuable chemicals using engineered organisms. The key objectives are to: Elucidate the structural mechanisms underlying the autoregulation of the GltAB-GudB enzyme complex in Bacillus subtilis, which regulates glutamate metabolism and impacts...

The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $500,000 Project Grant to the University of Wisconsin-Madison to develop a machine learning model for rapid assessment of technical and economic impacts of process perturbations in biomanufacturing. This 2-year project (8/1/2025 - 7/31/2027) aims to deliver a decision-making tool to enable predictable scale-up and consistently near-optimal performance for new fermentation processes, which is...

The National Institute of General Medical Sciences (NIGMS) awarded a $306,872 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Fluid Discovery, Inc., a San Francisco-based biotechnology company, to develop a "Universal Platform for Ultrahigh-Throughput Biocatalyst Evolution with Micro-Mass Spectrometry." The award supports the development of a commercial prototype for Fluid Discovery's novel screening platform, which combines scalable hardware,...