Cooperative Agreement DESC0021911

This National Science Foundation Project Grant of $255,261 awarded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) will fund the development of optimized extraction and projection optics for ion point sources. Steam Instruments Inc. will demonstrate technology advances in imaging mass spectrometry through this Small Business Innovation Research Phase I project. Specifically, the company aims to markedly improve mass resolving power to separate key mass...

This National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) Project Grant award of $258,586 to MSTM LLC will support the development of a new remote surface reader technology for direct sampling and analysis of surfaces using mass spectrometry. The goal is to demonstrate the feasibility and proof-of-concept of this surface reader device, which aims to enable rapid, accurate, and safe detection of various analytes, such as infectious...

This $640,232 federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program supports the development of a new holographic platform that enables high-speed, non-invasive 3D chemical imaging with broad biomedical applications. The key objectives are to demonstrate the feasibility of a new approach to achieving time-domain...

The National Institute of General Medical Sciences (NIGMS) awarded Trestle Optics LLC a $305,647 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to develop a novel photothermal microscopy system for non-destructive, high-resolution screening and sorting of microalgae to identify and enrich strains producing high-value polyunsaturated fatty acids. The project aims to engineer and prototype a microfluidic platform integrating photothermal imaging...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $934,875 Project Grant (CFDA 93.286: Discovery and Applied Research for Technological Innovations to Improve Human Health) to Rockefeller University to develop and demonstrate two fiber-based amplifier and detection systems (F-BADS) for laser scanning microscopy (LSM) applications. The first F-BADS will employ Raman amplification in multi-mode fibers to provide gain in the visible spectrum, and will be integrated...

Carnegie Mellon University was awarded a $385,000 Project Grant from the National Science Foundation under the Mathematical and Physical Sciences program (CFDA 47.049) to acquire a MALDI TOF/TOF mass spectrometer with imaging capabilities. The mass spectrometer will advance CMU's research and education efforts from August 1, 2021 through July 31, 2024 by enabling analysis of the spatial distribution of biomolecules at the microscopic level. NSF's Mathematical and Physical Sciences program...

This $1,574,994 Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) will support the acquisition of a state-of-the-art high-resolution tandem mass spectrometer at the University of California, Los Angeles (UCLA). The instrument will enable advanced structural characterization of a broad range of large biological and synthetic molecules, supporting over 11 NIH-funded research projects at UCLA. The mass spectrometer will provide...

The National Institutes of Health Office of the Director awarded Stanford University $3.8 million under the Research Infrastructure Programs grant program (CFDA 93.351) to acquire a new Orbitrap Tribrid mass spectrometry platform. For over 20 years, Stanford University Mass Spectrometry has served as the campus-wide shared proteomics resource, housing and maintaining mass spectrometry instruments to support numerous NIH-funded biomedical research projects spanning human development, degenerative...

This $769,749 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences will support the development of Fluorescence Enhanced Photothermal Infrared Spectroscopy (FE-PTIR) technology by Photothermal Spectroscopy Corp. The FE-PTIR technique aims to provide simultaneous fluorescence microscopy and sub-micron infrared spectroscopy to map the distribution of fluorescently labeled biomolecules within cells and tissues while also analyzing their chemical...

This $272,835 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, aims to develop a new Probe-Based Light Sheet Microscopy (PLSM) device and evaluate its clinical utility for in vivo imaging of the anal mucosa during cancer screening. The University of Arizona, as the prime awardee, will collaborate with researchers from Memorial...