Project Grant 84082601
- The National Science Foundation (NSF) awarded a $949,997 Project Grant to Iowa State University of Science and Technology under the Biological Sciences program (CFDA 47.074) to investigate the role of environmental factors in the development of antimicrobial resistance (AMR) in municipal wastewater treatment plants. The five-year research project, starting November 1, 2023, will conduct field, laboratory, and computational studies to determine how susceptible bacterial strains are replaced by...
- This $650,000 Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) to Virginia Polytechnic Institute & State University (Virginia Tech) supports research to investigate the role of environmental factors in the development of antibiotic resistance among bacteria in municipal wastewater treatment plants. The key products and services to be delivered under this 5-year award include: Conducting integrated field, laboratory, and computational studies to...
- This $999,618 project grant from the Department of Agriculture's National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) will fund the development of an antimicrobial resistance mitigation system incorporating engineered biochar adsorbents tailored to remove specific contaminants from reclaimed water. The University of California, Riverside will design a large-scale system to efficiently remove antibiotics and antibiotic...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $421,673 to William Marsh Rice University in Texas to develop computational tools and laboratory methods to identify and detect signature regions of antimicrobial resistant pathogens in wastewater. The goal is to improve wastewater surveillance of antimicrobial resistance, which is a critical public health challenge....
- The National Science Foundation Division of Emerging Frontiers awarded a $1,400,000 Project Grant under the Biological Sciences program (CFDA 47.074) to The Research Foundation For The State University Of New York, also known as Sponsored Projects Services, a non-profit research administration organization. This 5-year grant will fund collaborative research to investigate the role of environmental factors like temperature, heavy metals, and other contaminants in the development of...
- This $534,000 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research) to The Children's Hospital of Philadelphia on July 23, 2025. The grant supports the development of new systems to leverage wastewater surveillance for clinically applicable, proactive, and readily deployable monitoring of multidrug-resistant bacteria (MDRB), particularly extended-spectrum beta-lactam- and carbapenem-resistant Enterobacterales...
- This $999,984 project grant awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (CFDA 10.310 Agriculture and Food Research Initiative) aims to develop innovative and cost-effective recirculating water treatment methods to capture and degrade antibiotic residues in aquaponic systems. The key objectives are to: (A) develop a novel approach using a macroporous functionalized matrix to capture oxytetracycline residues from aquaponic water, and (B) evaluate...
- This $299,999 project grant, awarded by the U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), will develop a laboratory system to test three different disinfection methods. The goal is to identify the most effective approach for eliminating harmful, antibiotic-resistant bacteria from agricultural irrigation water sourced from treated wastewater. The project will also create...
- This Project Grant award, totaling $620,000.00, was provided by the U.S. Geological Survey (USGS) under the Assistance to State Water Resources Research Institutes program (CFDA 15.805). The purpose of the award is to determine the effects of per- and polyfluoroalkyl substances (PFAS) on microbiome health and neurotoxicity in bluegill, an economically and ecologically important fish species in the Great Lakes region. The key research activities include: 1) characterizing PFAS bioaccumulation and...
- This Project Grant award from the National Science Foundation (CFDA 47.041, Engineering) provides $280,000 to Temple University-Of The Commonwealth System Of Higher Education for a collaborative research project focused on mitigating antibiotic resistance. The key objectives are to: Understand the interactions between antibiotic resistance genes and carbon nanomaterials using reduced graphene oxide membranes; Enhance the electrostatic adsorption of antibiotic resistance genes on the modified...
DESCRIPTION:THE PURPOSE OF THE PROJECT IS TO QUANTIFY THE FATE OF ANTIBIOTIC-RESISTANT BACTERIA (ARB), GENES (ARGS) AND ANTIBIOTICS IN WASTEWATER TREATMENT UTILITIES ACROSS THE U.S. 40 WASTEWATER TREATMENT FACILITIES REPRESENTING VARIED GEOGRAPHICAL CONDITIONS, POPULATION DEMOGRAPHICS AND WASTEWATER SOURCES WILL BE SAMPLED WITH BOTH CULTURE AND MOLECULAR METHODS AS WELL AS SUSPECT SCREENING TO IDENTIFY ANTIBIOTIC COMPOUNDS. A META-ANALYSIS USING EXISTING METAGENOMIC DATA IN WASTEWATER IN THE LITERATURE WILL BE CONDUCTED TO UNDERSTAND THE IMPACTS OF SEASONAL/REGIONAL VARIATIONS AND CREATE A COMPREHENSIVE LIBRARY ON THE RESISTOME OF WASTEWATER. ACTIVITIES:40 WASTEWATER TREATMENT UTILITIES FROM 5 REGIONS ACROSS THE U.S. ACCOUNTING FOR VARIED GEOGRAPHICAL CONDITIONS, POPULATION DEMOGRAPHICS AND WASTEWATER SOURCES WILL BE SAMPLED FOR TWO YEARS. SAMPLES WILL BE COLLECTED THROUGHOUT THE WASTEWATER TREATMENT TRAIN TO INCLUDE BIOSOLIDS. BOTH CULTURE AND MOLECULAR METHODS WILL BE USED TO QUANTIFY ARB AND ARGS IN THE SAMPLES AND SUSPECT SCREENING WILL BE USED TO IDENTIFY ANTIBIOTIC COMPOUNDS IN THE SAMPLES. A SYSTEMATIC REVIEW OF METAGENOMIC DATA IN THE LITERATURE WILL CREATE A LIBRARY WHICH WILL BE USED TO CONDUCT A META-ANALYSIS PROVIDING A BETTER UNDERSTANDING OF THE SEASONAL/REGIONAL AND TREATMENT PROCESS EFFECTS ON ARB AND ARG LEVELS IN WASTEWATER. SUBRECIPIENT:NO SUBAWARDS ARE INCLUDED IN THIS ASSISTANCE AGREEMENT.OUTCOMES:KEY DELIVERABLES INCLUDE DATA ON THE ABUNDANCE OF ARB AND ARGS AS WELL AS ANTIBIOTICS IN WASTEWATER SAMPLES TO INCLUDE SAMPLING INFLUENT, SECONDARY EFFLUENT, TERTIARY EFFLUENT, FINAL EFFLUENT, RAW SLUDGE, AND TREATED BIOSOLIDS. SEPARATE REPORTS ON EACH PROJECT AIM WILL BE DEVELOPED INCLUDING DETAILS ON RESULTS SAMPLING, TESTING AND DATA ANALYSIS. A SYSTEMATIC REVIEW OF THE LITERATURE WILL BE CONDUCTED AND A METAANALYSIS WILL IDENTIFY SEASONAL/REGIONAL, AND TREATMENT PROCESS EFFECTS ON ANTIMICROBIAL RESISTANCE. TWO WEBINARS WILL BE DEVELOPED TO GUIDE UTILITIES AND REGULATORS ON EFFECTIVE TREATMENT PROCESS AND OPERATIONAL CONDITIONS FOR AMR REMOVAL. WORKSHOPS WILL BE HELD AT REGIONAL AND NATIONAL CONFERENCES TO DISSEMINATE RESULTS AND A PROJECT WEBSITE WILL BE DEVELOPED TO SHARE PROJECT INFORMATION AND DELIVERABLES. BENEFICIARIES INCLUDE THE PUBLIC, STATE AND LOCAL REGULATORS, WASTEWATER UTILITIES AND WATER QUALITY PROGRAM MANAGERS.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 5/7/25 | ||
| Not listed | $2.4m | 7/29/24 |