Not listed DESCRIPTION:THE GOAL OF THE PROPOSED RESEARCH IS TO BETTER CHARACTERIZE IMPORTANT EXPOSURE PATHWAYS OF PER- AND POLY-FLUOROALKYL SUBSTANCES (PFAS) AMONG VULNERABLE GROUPS, IN IMPACTED COMMUNITIES, AND IN THE GENERAL POPULATION. ACTIVITIES:THE PROJECT WILL COLLECT DATA THAT WILL ALLOW THE RECIPIENT TO EVALUATE HOW MUCH VARIABILITY IN PFAS SERUM LEVELS CAN BE EXPLAINED BY WATER CONSUMPTION AND OTHER RESIDENTIAL AND DIETARY EXPOSURE SOURCES/PATHWAYS SUCH AS INDOOR AIR. SUBRECIPIENT:A SUBAWARD WILL BE GIVEN TO INDIANA UNIVERSITY TO PERFORM PFAS ANALYSIS OF 50 PASSIVE INDOOR AIR AND 50 DUST SAMPLES COLLECTED IN PARTICIPANT HOMES, WITH THE ANALYSES TO BE CONDUCTED IN YEAR 1. OUTCOMES:THE ANTICIPATED DELIVERABLES ARE ANNUAL PROGRESS AND FINAL REPORTS. PROJECT OUTPUTS INCLUDE 1) EXPOSURE MEASUREMENTS (INDOOR AIR CONCENTRATIONS, HOUSEHOLD DUST CONCENTRATIONS) FOR 37 PFAS CHEMICALS AND QUESTIONNAIRE DATA FROM 50 HOMES CONCORDANT WITH BIOMONITORING DATA, 2) TOTAL FLUORINE (TF) AND EXTRACTABLE ORGANOFLUORINE (EOF) CONCENTRATIONS LEVELS IN 50 HOUSE DUST SAMPLES, 3) EVALUATED PROTOCOLS AND SOPS FOR MEASURING A TARGETED SET OF PFAS IN THE RESIDENTIAL ENVIRONMENT, INCLUDING DRINKING WATER; AND 4) PRELIMINARY ASSESSMENT OF RESIDENTIAL EXPOSURES, INCLUDING RELATIONSHIP BETWEEN MEASURED INDOOR AIR AND HOUSE DUST CONCENTRATIONS AND ASSOCIATIONS WITH HOUSING CHARACTERISTICS AND BEHAVIORS RELATED TO CONSUMER PRODUCTS WITHIN THE HOME. DIRECT BENEFICIARIES ARE STATE AND LOCAL PUBLIC HEALTH MANAGERS, THE SCIENTIFIC COMMUNITY, AND COMMUNITIES AFFECTED BY RESIDENTIAL PFAS EXPOSURE. $0 5/12/25 Not listed DESCRIPTION:THE GOAL OF THE PROPOSED RESEARCH IS TO BETTER CHARACTERIZE IMPORTANT EXPOSURE PATHWAYS OF PER- AND POLY-FLUOROALKYL SUBSTANCES (PFAS) AMONG VULNERABLE GROUPS, IN IMPACTED COMMUNITIES, AND IN THE GENERAL POPULATION. ACTIVITIES:THE PROJECT WILL COLLECT DATA THAT WILL ALLOW THE RECIPIENT TO EVALUATE HOW MUCH VARIABILITY IN PFAS SERUM LEVELS CAN BE EXPLAINED BY WATER CONSUMPTION AND OTHER RESIDENTIAL AND DIETARY EXPOSURE SOURCES/PATHWAYS SUCH AS INDOOR AIR. SUBRECIPIENT:A SUBAWARD WILL BE GIVEN TO INDIANA UNIVERSITY TO PERFORM PFAS ANALYSIS OF 50 PASSIVE INDOOR AIR AND 50 DUST SAMPLES COLLECTED IN PARTICIPANT HOMES, WITH THE ANALYSES TO BE CONDUCTED IN YEAR 1. OUTCOMES:THE ANTICIPATED DELIVERABLES ARE ANNUAL PROGRESS AND FINAL REPORTS. PROJECT OUTPUTS INCLUDE 1) EXPOSURE MEASUREMENTS (INDOOR AIR CONCENTRATIONS, HOUSEHOLD DUST CONCENTRATIONS) FOR 37 PFAS CHEMICALS AND QUESTIONNAIRE DATA FROM 50 HOMES CONCORDANT WITH BIOMONITORING DATA, 2) TOTAL FLUORINE (TF) AND EXTRACTABLE ORGANOFLUORINE (EOF) CONCENTRATIONS LEVELS IN 50 HOUSE DUST SAMPLES, 3) EVALUATED PROTOCOLS AND SOPS FOR MEASURING A TARGETED SET OF PFAS IN THE RESIDENTIAL ENVIRONMENT, INCLUDING DRINKING WATER; AND 4) PRELIMINARY ASSESSMENT OF RESIDENTIAL EXPOSURES, INCLUDING RELATIONSHIP BETWEEN MEASURED INDOOR AIR AND HOUSE DUST CONCENTRATIONS AND ASSOCIATIONS WITH HOUSING CHARACTERISTICS AND BEHAVIORS RELATED TO CONSUMER PRODUCTS WITHIN THE HOME. DIRECT BENEFICIARIES ARE STATE AND LOCAL PUBLIC HEALTH MANAGERS, THE SCIENTIFIC COMMUNITY, AND COMMUNITIES AFFECTED BY RESIDENTIAL PFAS EXPOSURE. $0 6/11/24 Not listed DESCRIPTION:THE GOAL OF THE PROPOSED RESEARCH IS TO BETTER CHARACTERIZE IMPORTANT EXPOSURE PATHWAYS OF PER- AND POLY-FLUOROALKYL SUBSTANCES (PFAS) AMONG VULNERABLE GROUPS, IN IMPACTED COMMUNITIES, AND IN THE GENERAL POPULATION. ACTIVITIES:THE PROJECT WILL COLLECT DATA THAT WILL ALLOW THE RECIPIENT TO EVALUATE HOW MUCH VARIABILITY IN PFAS SERUM LEVELS CAN BE EXPLAINED BY WATER CONSUMPTION AND OTHER RESIDENTIAL AND DIETARY EXPOSURE SOURCES/PATHWAYS SUCH AS INDOOR AIR. SUBRECIPIENT:A SUBAWARD WILL BE GIVEN TO INDIANA UNIVERSITY TO PERFORM PFAS ANALYSIS OF 50 PASSIVE INDOOR AIR AND 50 DUST SAMPLES COLLECTED IN PARTICIPANT HOMES, WITH THE ANALYSES TO BE CONDUCTED IN YEAR 1. OUTCOMES:THE ANTICIPATED DELIVERABLES ARE ANNUAL PROGRESS AND FINAL REPORTS. PROJECT OUTPUTS INCLUDE 1) EXPOSURE MEASUREMENTS (INDOOR AIR CONCENTRATIONS, HOUSEHOLD DUST CONCENTRATIONS) FOR 37 PFAS CHEMICALS AND QUESTIONNAIRE DATA FROM 50 HOMES CONCORDANT WITH BIOMONITORING DATA, 2) TOTAL FLUORINE (TF) AND EXTRACTABLE ORGANOFLUORINE (EOF) CONCENTRATIONS LEVELS IN 50 HOUSE DUST SAMPLES, 3) EVALUATED PROTOCOLS AND SOPS FOR MEASURING A TARGETED SET OF PFAS IN THE RESIDENTIAL ENVIRONMENT, INCLUDING DRINKING WATER; AND 4) PRELIMINARY ASSESSMENT OF RESIDENTIAL EXPOSURES, INCLUDING RELATIONSHIP BETWEEN MEASURED INDOOR AIR AND HOUSE DUST CONCENTRATIONS AND ASSOCIATIONS WITH HOUSING CHARACTERISTICS AND BEHAVIORS RELATED TO CONSUMER PRODUCTS WITHIN THE HOME. DIRECT BENEFICIARIES ARE STATE AND LOCAL PUBLIC HEALTH MANAGERS, THE SCIENTIFIC COMMUNITY, AND COMMUNITIES AFFECTED BY RESIDENTIAL PFAS EXPOSURE. $0 9/22/22 Not listed DESCRIPTION:THE GOAL OF THE PROPOSED RESEARCH IS TO BETTER CHARACTERIZE IMPORTANT EXPOSURE PATHWAYS OF PER- AND POLY-FLUOROALKYL SUBSTANCES (PFAS) AMONG VULNERABLE GROUPS, IN IMPACTED COMMUNITIES, AND IN THE GENERAL POPULATION. ACTIVITIES:THE PROJECT WILL COLLECT DATA THAT WILL ALLOW THE RECIPIENT TO EVALUATE HOW MUCH VARIABILITY IN PFAS SERUM LEVELS CAN BE EXPLAINED BY WATER CONSUMPTION AND OTHER RESIDENTIAL AND DIETARY EXPOSURE SOURCES/PATHWAYS SUCH AS INDOOR AIR. SUBRECIPIENT:A SUBAWARD WILL BE GIVEN TO INDIANA UNIVERSITY TO PERFORM PFAS ANALYSIS OF 50 PASSIVE INDOOR AIR AND 50 DUST SAMPLES COLLECTED IN PARTICIPANT HOMES, WITH THE ANALYSES TO BE CONDUCTED IN YEAR 1. OUTCOMES:THE ANTICIPATED DELIVERABLES ARE ANNUAL PROGRESS AND FINAL REPORTS. PROJECT OUTPUTS INCLUDE 1) EXPOSURE MEASUREMENTS (INDOOR AIR CONCENTRATIONS, HOUSEHOLD DUST CONCENTRATIONS) FOR 37 PFAS CHEMICALS AND QUESTIONNAIRE DATA FROM 50 HOMES CONCORDANT WITH BIOMONITORING DATA, 2) TOTAL FLUORINE (TF) AND EXTRACTABLE ORGANOFLUORINE (EOF) CONCENTRATIONS LEVELS IN 50 HOUSE DUST SAMPLES, 3) EVALUATED PROTOCOLS AND SOPS FOR MEASURING A TARGETED SET OF PFAS IN THE RESIDENTIAL ENVIRONMENT, INCLUDING DRINKING WATER; AND 4) PRELIMINARY ASSESSMENT OF RESIDENTIAL EXPOSURES, INCLUDING RELATIONSHIP BETWEEN MEASURED INDOOR AIR AND HOUSE DUST CONCENTRATIONS AND ASSOCIATIONS WITH HOUSING CHARACTERISTICS AND BEHAVIORS RELATED TO CONSUMER PRODUCTS WITHIN THE HOME. DIRECT BENEFICIARIES ARE STATE AND LOCAL PUBLIC HEALTH MANAGERS, THE SCIENTIFIC COMMUNITY, AND COMMUNITIES AFFECTED BY RESIDENTIAL PFAS EXPOSURE. $250.0k 6/29/22