The purpose of the biofabrication standards related test lab is to develop the infrastructure to apply a quality-by-design approach in the biofabrication industry for the standardization of assay…

Active Project Grant Awarded Last action

Award ID
60NANB24D172
Recipient
Awarding agency
Obligated
$1,200,000

Award facts

Assistance listing
11.617 Congressionally-Identified Projects
Completion date 69% complete
Originally
Place of performance
Manchester, NH 03101, USA

Award details come from USAspending.gov.

Description

Activities
The activities of this project are split into the assay development and standard development components, using the glucose stimulated insulin secretion (gsis) assay as their model. Under assay development, armi will simplify the gsis assay, making the assay compatible for automation. They will also determine the sources of variability that affects the accuracy of the modified assay. Under standards development, armi will leverage the participation of subject matter experts to help inform the scope and content of a documentary standard as well as to develop an implementation training course for the standard, where trainees will be able to obtain a microcredential. Armi will engage the biofabrication ecosystem in their project in multiple ways. Armi will engage with the biosystems and biomaterials division at NIST to exchange knowledge on NIST's work on the prototype cell assay measurement platform. Additionally, they will engage breakthrough T1D (breakthrough type 1 diabetes) and the standards coordinating body to optimize the development and standardization of the gsis assay.
Expected outcomes
The main outcome of this project is to provide a simplified, standardized gsis assay that will allow for an improvement in repeatability and reproducibility of the gsis assay, a protocol in which could be extrapolated to other cell and tissue based assays as well.
Intended beneficiaries
The results from this grant will benefit researchers, patients, and clinicians who rely on similar cell and tissue-based assays.
Subrecipient activities
The recipient does not intend to subaward funds.

Transactions

Action Obligated Date
Amendment $0
Original award $1,200,000

Quick answers

Who received award 60NANB24D172?

60NANB24D172 was awarded to Advanced Regenerative Manufacturing Institute Inc. by National Institute of Standards and Technology (Department of Commerce) on October 1, 2024.

How much is award 60NANB24D172 worth?

$1,200,000 has been obligated on 60NANB24D172.

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