Project Grant 5920905001F0

The Department of Agriculture's National Institute of Food and Agriculture awarded Kansas State University $650,000 under the Agriculture and Food Research Initiative competitive grants program to develop improved vaccines for bovine respiratory disease complex. With funding through May 2026, the university aims to generate new knowledge needed to design vaccines capable of protecting calves against multiple strains of Bovine parainfluenza virus 3 and Bovine viral diarrhea virus. Researchers...

This Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA), under the Agriculture and Food Research Initiative (AFRI) CFDA program, provides $650,000 to the University of Missouri System to develop a novel vaccine against bovine tuberculosis (BTB) caused by Mycobacterium tuberculosis variant bovis (M. bovis). The goal is to create a recombinant Bacillus subtilis spore-based mucosal vaccine that can elicit protective immune responses...

The U.S. Department of Agriculture (USDA) awarded a $300,000 grant under the Agriculture and Food Research Initiative (AFRI) program to Oklahoma State University (OSU) to develop a novel single-cycle vaccine against bovine respiratory syncytial virus (BRSV). The project aims to pioneer the development of two single-cycle BRSV vaccine prototypes: an 'MNull' vaccine that lacks the essential matrix protein, and a 'PRef' vaccine with a modified fusion protein. OSU will evaluate the immunogenicity...

The Department of Agriculture's National Institute of Food and Agriculture awarded $530,000 under the Agriculture and Food Research Initiative competitive grants program to develop a trivalent vaccine that protects against Marek's disease, Newcastle disease, and infectious laryngotracheitis in poultry. With a completion date of April 30, 2026, this Project Grant will fund research at the Agricultural Research Service's Southeast Area location in Stoneville, MS to design a single vaccine using...

The U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) awarded a $800,000 Project Grant under the Agriculture and Food Research Initiative (AFRI) program to Washington State University (WSU). The grant aims to develop a vaccine against anaplasmosis, a prevalent tick-borne infection in cattle that causes significant morbidity and an estimated $300 million in annual economic losses in the U.S. The project will test the protective capacity of outer membrane...

Long Island University received a three-year, $627,000 Project Grant award from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The grant will fund research to develop an improved vaccine for bovine respiratory disease (BRD) in cattle. BRD costs the U.S. beef industry over $3 billion annually. Current commercial vaccines have limited effectiveness. The university will generate...

The U.S. Department of Agriculture (USDA) awarded a $650,000 project grant to Oklahoma State University (OSU) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The grant aims to identify cellular and viral genes that induce reactivation of Bovine Herpesvirus 1 (BoHV-1) from latency in cattle. Understanding the mechanisms of BoHV-1 reactivation will allow the development of improved vaccine strategies to reduce the spread of the virus and incidence of Bovine...

The University of Missouri System, under a $650,000 project grant from the USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program, is developing safe and effective live attenuated swine influenza vaccines using Newcastle disease virus (NDV) as the vector. The project aims to address the challenges with current swine influenza vaccines, which often fail to provide cross-protection against diverse virus strains. The key products and...

This $300,000 Project Grant awarded by the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program supports research at Texas Tech University to investigate the impact of Bovine Leukemia Virus (BLV) on dairy cow immune systems. The project will employ advanced single-cell RNA sequencing techniques to examine changes in blood cell function at the molecular level in BLV-infected cattle. The goal is to uncover specific weaknesses in...

This Project Grant award from the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) (CFDA 10.310) supports research to study the effects of Bovine Viral Diarrhea Virus (BVDV) on the thymus and T-cell receptors in cattle. The $300,000 award to Oklahoma State University aims to better understand how BVDV damages the thymus, a key organ for T-cell development, and impacts T-cell receptor diversity, which is crucial for an effective...