Project Grant 2619620
Award Date 7/15/26
Completion Date 6/30/29
Dollars Obligated $286K
Funding Federal Agency
Awarding Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Springfield, MO 65897, USA
Similar Awards
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Mississippi State University $669,055 on July 15, 2026, under the Biological Sciences program (CFDA 47.074) to investigate how DNA damage affects transcript fidelity and cellular function. The project will analyze the interplay between DNA replication and transcription fidelity through three core objectives. First, it will identify the role of DNA and RNA damage in transcript fidelity using rolling-circle...
- This $900,000 federal Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports a collaborative research project led by North Carolina State University to unravel the mechanisms behind the workings of the DNA mismatch repair systems. The research aims to elucidate the role of atypical nucleic acid structures, such as three-way junctions and R-loops, in driving the expansion of simple sequence repeats (SSRs) within the genome, which is a...
- This federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $796,823 to the University of Missouri System to conduct research on the genetic and molecular mechanisms behind meiotic silencing by unpaired DNA. The research aims to better understand how organisms use RNA-based gene silencing systems to identify and suppress the expression of DNA segments lacking a pairing partner, which can indicate the presence of viruses or...
- This $150,000 Project Grant awarded by the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program funds research at Vanderbilt University to elucidate the molecular mechanisms of DNA repair by a newly discovered bacterial enzyme. The project aims to understand how this enzyme protects microbes against toxic natural products, with the long-term goals of elucidating bacterial interstrand DNA crosslink repair pathways and discovering new genotoxic agents with...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Brown University $1.2 million on July 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate mechanisms of base excision repair in nucleosomes. The project examines how the physical organization of DNA in chromatin influences the ability of base excision repair (BER) enzymes to locate and repair damaged bases. Research will define how chromatin architectural proteins and chromatin...
- This federal Project Grant award, valued at $541,574.00 and awarded on January 15, 2025, is funded by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) Federal Grant Program. The project, titled "COLLABORATIVE RESEARCH: NSF/MCB-BSF: THE EFFECT OF TRANSCRIPTION FACTOR BINDING ON UV LESION ACCUMULATION", aims to determine whether transcription factor binding to DNA makes it more susceptible to damage or impedes DNA repair, leading to increased genomic...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Brandeis University $370,052 on August 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate how intrinsically disordered regions in proteins regulate the search and binding of heterochromatin-associated proteins in living cells. The research aims to determine how dynamic recruitment and retention of histone H3 lysine 9 methylation-binding proteins establish stable and heritable gene...
- This Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), provides $300,000 to the University of Kansas Center for Research Inc. from February 1, 2023 to January 31, 2025. The award will support research investigating delivery and trafficking of DNA introduced to cells from environmental sources using the genetically tractable organism Caenorhabditis elegans. The project aims to gain new...
- This $393,263 National Science Foundation Division of Chemistry Project Grant will support collaborative research between the University of California, Davis and the University of Utah to study DNA repair mechanisms. The research aims to apply a chemical biology approach to reveal insights into base excision repair glycosylases that identify and initiate repair of rare DNA bases with subtle damage. Specifically, the team will develop transition state mimics to test the idea that evolutionarily...
- The National Institute of General Medical Sciences awarded the University of Arkansas for Medical Sciences $420,750 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research revealing DNA polymerase molecular strategies in end-joining double strand break repair. The project integrates structural biology, mechanistic biochemistry, biophysics, computational methods, and molecular biology to uncover how DNA polymerases and nucleases process and...