Project Grant 2603025
- The National Science Foundation Directorate for Mathematical and Physical Sciences awarded Howard University $199,460 on September 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) for a collaborative research project developing a rigorous framework for mathematicians and artificial intelligence systems to accelerate discovery in number theory and combinatorics. The work establishes a four-phase iterative workflow: generating and curating large datasets of complex...
- The National Science Foundation Office of Integrative Activities awarded Howard University $549,681 on September 1, 2026, under the Integrative Activities program (CFDA 47.083) to establish fundamental understanding of how biomass characteristics impact interfacial adhesion with polymer matrices and influence composite processability and performance. The research integrates systematic biomass chemical modification, multiscale characterization, and composite manufacturing to generate...
- The National Institute of Allergy and Infectious Diseases, a component of the Department of Health and Human Services, awarded Howard University $193,125 on July 22, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award funds investigation of antiviral factors that restrict HIV-1 infection in patients with systemic lupus erythematosus (SLE). The research examines how elevated levels of interleukin-16, type I interferons, and dysregulated iron homeostasis in...
- This $150,607 National Science Foundation project grant will support a research community development project focused on collaborative research related to knowledge of HIV/AIDS. Led by the University of Washington with a completion date of August 2026, the project aims to bring together social scientific and humanistic scholars within the interdisciplinary field of science and technology studies. Key activities over the three-year period will include organizing three annual workshops around...
- This $644,524 Project Grant award from the National Science Foundation's (NSF) Integrative Activities (CFDA 47.083) program supports a collaborative research project between Howard University and North Carolina A&T State University. The project aims to identify the dynamic structure of the progression to type 2 diabetes (T2D) using mathematical models. Key activities include: Constructing a theoretical threshold to distinguish between diabetes and non-diabetes states, validated using...
- This $125,888 Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research by Yale University to investigate how the mechanical properties of host cells impact the infection and integration of the human immunodeficiency virus (HIV). The key objectives are to: 1) examine how HIV infection affects the mechanical and morphological attributes of the host cell nucleus, and 2) determine how the mechanical environment of the...
- The National Institute of Allergy and Infectious Diseases awarded The Washington University $791,065 on August 18, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to fund research into the role of capsid interactions with viral RNA genome in assembly of HIV-1 cores. The research investigates how HIV-1 capsid proteins and viral RNA genome components organize during viral maturation. The study will clarify structural mechanisms underlying HIV-1 core formation,...
- The National Institute of General Medical Sciences awarded Howard University $566,094 on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop computational models predicting gene essentiality and identifying functional protein substructures using graph attention networks. The project, running through April 30, 2029, and performed in Washington, DC, will create advanced machine learning frameworks incorporating interpretable biochemical features such...
- The National Institute of Allergy and Infectious Diseases awarded Massachusetts Institute of Technology (MIT) $553,136 on August 17, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research visualizing HIV-1 capsid passage through the nuclear pore complex. The funded work addresses how HIV-1 traverses the nuclear pore complex during viral entry into the cell nucleus, a critical stage in the infection process preceding uncoating, reverse transcription, and...
- The National Institute of Allergy and Infectious Diseases awarded The Johns Hopkins University $781,073 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop interventions that silence HIV-1 and reduce viral reservoir persistence following antiretroviral therapy initiation. The research develops a new intervention using ectopic expression of an HIV-1-encoded antisense transcript (AST) delivered before ART initiation or restart. The work aims to...
The National Science Foundation Office of Integrative Activities awarded Howard University $1,065,309 on September 1, 2026, under the Integrative Activities program (CFDA 47.083) to develop computational and mathematical methods for modeling HIV drug resistance to the long-acting injectable cabotegravir (CAB-LA) used in treatment and pre-exposure prophylaxis. The project integrates molecular, evolutionary, and immunological insights into a unified mathematical framework combining machine learning, biochemical data, evolutionary theory, and virtual clinical trials to advance prediction of drug resistance and inform more effective prevention strategies. The research generates new computational methods addressing real-world complexity in HIV treatment and generates open-source software and educational materials making advanced modeling tools accessible to researchers and students. The project builds workforce capacity by engaging graduate and undergraduate students at Howard University and Loyola Marymount University in developing skills in mathematical modeling, computation, and data analysis. Cross-institutional training expands participation in computational research, strengthens collaborations between institutions, and prepares students to address emerging challenges in biomedical science and public health. Performance is located in Washington, DC 20059. The project runs through August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.1m | 8/14/26 |