Project Grant 2602728
- The National Science Foundation (NSF) Office of Integrative Activities awarded a $738,400 Project Grant to the Morehouse School of Medicine (MSM) to investigate the synergistic effects of engineered extracellular vesicles (EVs) from stem cells and macrophages on angiogenesis, the formation of new blood vessels. The 4-year project will explore how EVs from different cell types cooperatively regulate normal and pathological angiogenesis, as well as develop novel EV-based therapeutic strategies....
- The Morehouse School of Medicine (MSM) received a $996,072 Project Grant award from the National Science Foundation (NSF) Integrative Activities (CFDA 47.083) program. The grant will support research to investigate the role of the acid-sensing ion channel 1A (ASIC1A) in neuronal development and maturation. Through a combination of molecular biology, imaging, electrophysiology, pharmacology, proteomics, and in vitro/in vivo models, the project aims to systematically examine how ASIC1A contributes...
- This $474,385 National Science Foundation Office of Integrative Activities Project Grant will fund research at Southern University and A&M College from July 2022 through June 2025 to elucidate conserved eukaryotic nucleolar and ribosomal stress mechanisms. The research aims to identify common pathways that link cell growth to the cell cycle and subsequent stress responses when growth is arrested in unicellular and multicellular eukaryotes. The researchers will systematically express and...
- The University of Texas Southwestern Medical Center in Dallas, TX will receive $950,000 in project grant funding from the National Science Foundation under the Biological Sciences program (CFDA 47.074) for research titled "ACTIN REGULATION OF CD36 RECEPTOR ORGANIZATION AND SIGNALING" from August 1, 2021 to July 31, 2025. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the nation's scientific enterprise through increasing...
- The National Science Foundation (NSF) Office of Integrative Activities awarded a $297,393 Project Grant to Western Kentucky University (WKU) to acquire a Fluorescence-Activated Cell Sorter (FACS) instrument. The grant will enable WKU's diverse undergraduate and master's student population, as well as high school students, to gain hands-on skills in modern cell analysis technology and conduct research across various disciplines, including microbiology, immunology, cancer biology, and...
- The National Science Foundation (NSF), through its Integrative Activities program (CFDA 47.083), awarded a $300,000 project grant to the University of Mississippi to investigate the function of a broadly conserved bacterial protein and its role in pilus biogenesis. This 3-year project, spanning from February 2025 to January 2028, aims to characterize the mechanisms by which the unknown protein BRESU_2828 influences the synthesis of bacterial pili, which are structures used for attachment and...
- The National Science Foundation (NSF) Office of Integrative Activities awarded a $429,371 Project Grant to the University of Memphis to acquire a BD FACSMelody Fluorescence-Activated Cell Sorter (FACS) instrument. This FACS will enhance a broad range of multidisciplinary and collaborative biological research at the University of Memphis and at other Memphis-area research institutions, while also expanding training opportunities for undergraduates, graduate students, and postdoctoral researchers....
- This $970,384 Project Grant award from the National Science Foundation (NSF) Integrative Activities (IA) program (CFDA 47.083) supports research at Winston-Salem State University (WSSU), a historically Black college and university, to investigate the role of mitochondrial damage-associated molecular patterns (mtDAMPs) in driving sterile inflammation following muscle contraction-induced injury. The key objectives are to elucidate the molecular mechanisms by which mtDAMPs mediate the...
- The National Science Foundation (NSF) awarded a $131,176 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Utah Office of Sponsored Projects Division. The grant funds collaborative research on how a class of proteins called alpha-arrestins regulate nutrient transport and metabolism in eukaryotic cells. Key objectives include determining how loss of alpha-arrestins impacts cellular physiology and mitochondrial function, and developing undergraduate research...
- The National Science Foundation Office of Integrative Activities awarded Howard University $551,029 on August 15, 2026, under the Integrative Activities program (CFDA 47.083) to advance research on novel polysaccharides for cell-specific oral drug delivery and to establish professional development programming for undergraduate and graduate students. The project will study how polymer structure affects the bioavailability and site-specific delivery of therapeutics through the gastrointestinal...
The National Science Foundation Office of Integrative Activities awarded The Morehouse School of Medicine $985,378 on August 1, 2026, under the Integrative Activities program (CFDA 47.083) to investigate molecular mechanisms of fatty acid uptake and trafficking in renal tubule epithelial cells. The research examines how kidney tubular epithelial cells use intracellular organelles to respond to energy and nutrient overloads, with focus on lipotoxicity—cellular dysfunction caused by accumulation of saturated fatty acids, particularly palmitate. The project applies biochemical, molecular biology, genetics, and genomics approaches to determine how signaling pathway components communicate to maintain cellular homeostasis and to advance understanding of molecular mediators and pathways involved in fatty acid uptake, trafficking, and metabolism. The work includes educational and training opportunities for middle school, high school, undergraduate, and graduate students in biological sciences to expand the STEM workforce. Performance occurs in Atlanta, Georgia, with a period of performance from August 1, 2026, through July 31, 2030. The Integrative Activities program supports capacity-building and broadened participation in research and education to enhance the Nation's research competitiveness and develop critical infrastructure for the STEM enterprise.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $985.4k | 7/30/26 |