Project Grant 2527124
- This $276,000 National Science Foundation award under the Biological Sciences program (CFDA 47.074) will fund research and training from August 1, 2022 to July 31, 2024. The fellowship recipient will conduct integrative research investigating the interaction of genomes, environments and phenotypes in evolutionary biology. Specifically, the fellow will study mechanisms connecting short-term plastic behavioral responses to long-term evolutionary change. Using a pupfish system with specialist and...
- The National Science Foundation (NSF) awarded a $494,261 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research on frog skin evolution and adaptations. The project aims to: 1) quantify how frog skin has evolved over the past 200 million years in response to abiotic and biotic factors, 2) experimentally test the ability of anuran skin to decouple respiration and water loss, and 3) incorporate...
- The National Science Foundation awarded a $315,757 Project Grant to Simmons University under the Biological Sciences program (CFDA 47.074) for the period of April 1, 2021 through March 31, 2024. The grant aims to advance understanding of the developmental genetics underlying limb initiation in amphibians. Specifically, the university will conduct research to determine the cellular origins and molecular mechanisms that drive limb formation in metamorphosing frogs. Researchers will use...
- The National Science Foundation Division of Integrative Organismal Systems awarded the University of Virginia $628,049 on April 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate the evolutionary biomechanics and functional morphology of salamander locomotion. The project examines how habitat preference and developmental strategy affect the relationship between tissue structure and whole-organism performance in salamanders, integrating physiology, engineering, and...
- The National Science Foundation Division of Integrative Organismal Systems awarded a $980,000 Project Grant to The Washington University to support research examining neuronal plasticity and the evolvability of behavior through September 2026. Funded under the Biological Sciences program (CFDA 47.074), this award will allow researchers to test the hypothesis that activity-dependent wiring changes in response to altered sensory feedback drive coordinated modifications between peripheral organs...
- The National Science Foundation (NSF) awarded a $426,255 project grant under the Biological Sciences program (CFDA 47.074) to the University of Texas at Austin to investigate the evolution of immune system development across amphibian life stages. The key objectives are to: (1) use mathematical models and empirical data to predict how evolutionary history, pathogens, and environment influence T cell diversity within and among frog life stages; (2) quantify T cell receptor diversity across...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of Massachusetts Boston $440,000 on July 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate mRNA regulation mechanisms that control neuronal function across distant animal species, particularly ctenophores that diverged from other animals over 800 million years ago. The research team will examine whether mechanisms regulating protein generation from specific mRNAs in...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded the University of Utah $1.587 million on July 15, 2026, under the Biological Sciences program (CFDA 47.074) to investigate mechanisms of fast rhythm generation in vertebrate neural circuits. The research team will use high-density brain recording technologies and AI-assisted modeling to study how the African clawed frog brain generates fast motor rhythms with millisecond precision, using an isolated brain...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1,197,230 to The Trustees of Columbia University in the City of New York on June 1, 2026, under the Biological Sciences program (CFDA 47.074). The award funds research investigating the neural basis for social prediction in weakly electric mormyrid fish—specifically how the nervous system learns to predict sensory consequences of actions produced by other individuals and which cells and circuits execute...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $750,000.00 will investigate how the central nervous system of vertebrates produces coordinated leg movements. Specifically, the project will use the turtle spinal cord as a model system to pharmacologically perturb inhibitory and excitatory neurotransmitter receptors to understand how the spinal cord generates and selects appropriate motor outputs for swimming, scratching, and leg withdrawal...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded $262,753 to Smith College on September 1, 2026, under the Biological Sciences program (CFDA 47.074) to investigate spinal neuron diversity and the evolution of novel motor behavior in frogs. The research examines how the nervous system evolves to produce new and complex behaviors by studying foot-flagging frogs that perform elaborate hind-limb communication displays. The project identifies genes and specific cell types associated with the evolution of this movement, comparing multiple frog species to determine whether evolution repeatedly arrives at similar biological solutions or employs different mechanisms to achieve the same outcome. The work focuses on the spinal cord, the critical nervous system component controlling movement in all vertebrates. Foot-flagging species possess substantially more spinal nerve cells involved in coordinating hind limb movement than closely related non-displaying species. Understanding how spinal circuits change over evolutionary time advances fundamental knowledge about neural development and spinal circuit organization, with potential applications to research on movement disorders and spinal cord function. The project runs from September 1, 2026, through August 31, 2029, with performance at Smith College in Northampton, Massachusetts. Broader impacts include supporting a mid-career investigator to expand skills in cutting-edge imaging and computational analysis, and providing hands-on research training for undergraduate students.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $262.8k | 7/28/26 |