Project Grant 2523434
- This National Science Foundation (NSF) Project Grant, under the Biological Sciences program (CFDA 47.074), provides $240,000 in funding from February 1, 2024 to January 31, 2027 to support a postdoctoral research fellowship focused on investigating a novel circadian time-keeping mechanism revealed by environmental manipulation. The research plan aims to identify the location in the brain and the mechanism of a non-canonical clock that can rescue daily rhythms in mice with disrupted central clock...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program has awarded a 4-year, $366,378 Project Grant to the Trustees of Indiana University to conduct research on the neuronal basis of sexual dimorphism in the circadian system of the fruit fly Drosophila. The project aims to elucidate how differences in the architecture of the Drosophila circadian system underlie sex differences in sleep/wake cycles and timekeeping robustness. The research will leverage...
- The National Institute of General Medical Sciences (NIGMS) awarded a $435,126 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Chicago. The grant, titled "Connecting Circadian Clock Dynamics to Metabolism and Fitness," will support research to understand the biophysical basis of circadian rhythms and their connection to metabolism, with the goal of recreating an oscillatory system using purified components. Key activities...
- This $438,915 project grant was awarded by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training federal grant program (CFDA 93.859), to Florida State University (FSU). The overarching goal of this 5-year project is to advance scientific understanding of the genetic and molecular basis of circadian rhythms and sleep disorders in mammalian models and humans. Specifically, the research aims to: 1) Identify and characterize the genetic...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $361,454.00 in funding to the University of Massachusetts Boston to investigate the molecular mechanisms underlying circadian compensation in eukaryotic organisms. The overarching objectives are to: 1) define cellular effectors and metabolic variables that control circadian oscillations in fungi and test for...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $451,250.00 to Children's Hospital Medical Center in Cincinnati, Ohio to investigate the molecular basis of circadian and sensory integration in neuronal clocks. The research aims to understand how gene expression in brain oscillators is affected when clock gene rhythms are disrupted in the suprachiasmatic nucleus,...
- The National Science Foundation (NSF) awarded a $7,394,696 Project Grant under the STEM Education (CFDA 47.076) program to the Morehouse School of Medicine, Inc. (MSM) to establish a world-class research center for studying circadian rhythms and sleep. The 5-year project, titled "CREST PHASE I: CENTER FOR CIRCADIAN RHYTHMICITY AND SLEEP HOMEOSTASIS", aims to investigate how circadian disruptions affect the body, focusing on identifying the neuronal mechanisms responsible for...
- This $380,089.00 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports fundamental research on the molecular mechanisms underlying circadian rhythms. The project aims to determine the mechanisms that define the period and light-dependent phase shift of circadian rhythms, which are critical for aligning cellular and physiological processes with external environments. By...
- This three-year Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $778,435 to the University of Massachusetts Medical School to investigate the mechanisms underlying circatidal rhythms in the coastal crustacean Parhyale hawaiensis. The researchers will work to elucidate the fundamental properties and molecular underpinnings of circatidal clocks, which allow organisms to anticipate tidal changes similar to circadian clocks and daily...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $1,000,000 in funding to Tufts University to study how a factor secreted from muscle regulates levels of neurotransmitter receptors in neurons that control movement in the roundworm Caenorhabditis elegans. The research aims to advance scientific understanding of how muscle releases factors that signal to the brain to control communication between neurons, which may provide...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $700,000 to the University of Wisconsin-Whitewater will investigate the effects of circadian clock components on early muscle development in the frog Xenopus laevis. The principal investigator hypothesizes that two circadian clock components, BMAL1 and NR1D1, impact metabolism and gene expression during the specification of dorsal mesoderm, which gives rise to skeletal muscle. Proposed experiments will examine how loss of these circadian clock components alters various early stages of muscle development, and whether downstream targets of the adult circadian clock also impact muscle formation. The award will support undergraduate laboratory experiences in genome editing and metabolism, as well as training of a postdoctoral researcher and outreach to K-12 students and the public. This project aims to elucidate the early developmental impacts of circadian clock components, which could have broader implications for understanding how disruptions to circadian rhythms can affect organismal health and well-being.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $700.0k | 8/6/25 |