Project Grant 2505623
- This federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $193,684.00 to the University of Georgia Research Foundation to investigate how the ciliate protozoan Tetrahymena thermophila organizes its cellular structures in a complex, circumferential pattern. The 4-year research project explores the role of polo kinases in maintaining this chiral asymmetry, providing insights into organizational mechanisms beyond the...
- This National Science Foundation project grant award of $138,000 provides funding from November 1, 2022 through October 31, 2024 to support research and training under the Biological Sciences federal grant program (CFDA 47.074). The award will fund a postdoctoral fellowship to investigate how gene-environment interactions have shaped the repeated evolution of differentiated multicellularity. The fellow will employ single-cell transcriptomics and comparative analyses to examine how...
- This $493,073 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports collaborative research at the University of California, Santa Barbara (UCSB) on the evolutionary processes that enable a genus of ciliates known as Mesodinium to acquire and maintain phototrophy through organelle sequestration. The 3-year project will use comparative cellular, metabolic, and genetic analyses to understand the adaptations that allow some Mesodinium species to...
- The Salk Institute for Biological Studies was awarded a three-year, $881,161 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) beginning July 1, 2021 to conduct research on Cross-Chiral Genetic Systems. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the national scientific enterprise through increasing knowledge and understanding of major problems. As part of this grant, The Salk Institute will...
- This National Science Foundation Project Grant of $276,000 supports a postdoctoral fellowship in biology for fiscal years 2022 through 2024 under the Biological Sciences program (CFDA 47.074). The fellowship will fund research and training investigating the spatiotemporal coordination of cell and chloroplast division in the green alga Chlamydomonas reinhardtii. Using gene editing, live cell microscopy, and other techniques, the fellow will test hypotheses about cytoskeletal structures...
- This National Science Foundation Project Grant award of $138,000 provides funding from August 1, 2022 to July 31, 2024 to support an NSF Postdoctoral Fellowship in Biology. The fellowship will fund research and training under the Biological Sciences program (CFDA 47.074) to define the biochemical mechanisms of microtubule shrinking and nucleation through innovative experiments and simulations. The fellow will combine wet lab experiments with computational simulations to determine how new...
- This $309,797 Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) will support a two-pronged research effort to study the emergence of long-range coherence in motile microorganismal systems with quenched disorder. The first component involves experimental studies of bacteria, amoeba, and bladder cancer cells in disordered environments to understand how self-propelled motion leads to large-scale collective behavior. The...
- This Project Grant award for $1,132,274 from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program will support research to understand how single cells are able to move through constrained environments by studying the cytoskeletal regulation of cell migration. The primary aim is to investigate how evolutionarily conserved septin proteins function to enable cells, from nematodes to humans, to squeeze through tight spaces. This will involve developing...
- This federal Project Grant award of $946,895 from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences (CFDA 47.074 Biological Sciences) will fund research to advance the understanding of protein phosphorylation and its role in coordinating cell division. The project aims to identify new enzymes that carry out phosphorylation and the substrate proteins they modify to ensure proper cell division. Researchers will employ computational, biochemical, proteomic,...
- This Project Grant award of $891,897 from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program supports a collaborative research effort to study the multiscale mechanics of septin assembly and curvature sensing in biological cells. The research, conducted by the University of North Carolina at Chapel Hill (UNC-CH), aims to determine how cells can sense micron-scale geometry using nanometer-scale septin proteins. Key objectives include investigating...
This Project Grant award of $682,000 from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program supports a collaborative research investigation led by St. Olaf College into the role of polo kinases in maintaining chiral asymmetry in the ciliate Tetrahymena thermophila. The project aims to explore how this single-celled protozoan organism is able to achieve a high degree of organizational complexity, including the development of a 360-degree circumferential patterning of its cellular structures, rivaling that seen in higher organisms. By studying the deployment of genes shared with humans, the researchers seek to uncover new mechanisms for intracellular patterning in living cells. The award will fund this research over a four-year period from September 2025 through August 2029. Additionally, the project provides an attractive model system for training undergraduate students in advanced microscopy and scientific research through summer programs and laboratory courses at St. Olaf College.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $682.0k | 8/18/25 |