Project Grant 20224000037061

Award Date 5/15/22
Completion Date 1/14/23
Dollars Obligated $175K
Federal Grant Program
10.212
Assistance Type
Project Grant
Place of Performance
MONTGOMRY VLG, MD 20877, USA
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Silvec Biologics Inc. was awarded a $174,964 Small Business Innovation Research (SBIR) Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture to develop a proprietary process to control fungi using RNA interference. The SBIR program aims to support scientific innovation to build a strong national economy.

Under the award, Silvec will pursue four key objectives through January 2023. The company will identify small interfering RNAs compatible with its delivery vector that can silence critical genes in the fungus Botrytis cinerea in vitro. Silvec will also demonstrate that its vector-derived siRNAs can suppress the pathogenicity of B. cinerea in Nicotiana benthamiana in the laboratory. If successful in achieving the first two Phase I objectives, Silvec will then evaluate controlling B. cinerea preharvest and postharvest diseases in grapevines through greenhouse and field trials in Phase II. The results could transform U.S. agriculture by providing an environmentally-friendly alternative to conventional fungicides and saving growers billions annually from reduced crop losses and increased yields.

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