Project Grant 201433610219061

The Department of Agriculture's National Institute of Food and Agriculture awarded Kansas State University $650,000 under the Agriculture and Food Research Initiative competitive grants program to develop improved vaccines for bovine respiratory disease complex. With funding through May 2026, the university aims to generate new knowledge needed to design vaccines capable of protecting calves against multiple strains of Bovine parainfluenza virus 3 and Bovine viral diarrhea virus. Researchers...

This Project Grant award from the National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), will provide $674,963 to Microbiotix, Inc. to advance the development of filociclovir as a treatment for adenoviral conjunctivitis and acute keratoconjunctivitis. The key objectives are to finalize the eye drop formulation, complete IND-enabling preclinical studies, and prepare the Investigational New Drug (IND) application to support human clinical trials. This includes formulation...

The Department of Agriculture's National Institute of Food and Agriculture awarded $530,000 under the Agriculture and Food Research Initiative competitive grants program to develop a trivalent vaccine that protects against Marek's disease, Newcastle disease, and infectious laryngotracheitis in poultry. With a completion date of April 30, 2026, this Project Grant will fund research at the Agricultural Research Service's Southeast Area location in Stoneville, MS to design a single vaccine using...

The University of Missouri System, under a $650,000 project grant from the USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program, is developing safe and effective live attenuated swine influenza vaccines using Newcastle disease virus (NDV) as the vector. The project aims to address the challenges with current swine influenza vaccines, which often fail to provide cross-protection against diverse virus strains. The key products and...

This $610,000 Project Grant from the US Department of Agriculture's National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) competitive grants program will support research at Texas A&M Agrilife Research to develop an mRNA-based approach to prevent pneumonia in foals caused by Rhodococcus equi. The objectives are to demonstrate in-vitro that mRNA-encoded antibodies can recognize and kill R. equi bacteria, optimize dosing and formulation of the mRNA...

The Department of Agriculture's National Institute of Food and Agriculture awarded a $299,941 Project Grant to Texas A&M Agrilife Research under the Agriculture and Food Research Initiative competitive grants program. The grant will fund research from March 2022 to February 2025 to evaluate the timing of bovine viral diarrhea virus and bovine herpesvirus vaccinations in cattle herds. The research aims to determine the optimal interval between vaccination and the start of breeding seasons...

The U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) awarded a $800,000 Project Grant under the Agriculture and Food Research Initiative (AFRI) program to Washington State University (WSU). The grant aims to develop a vaccine against anaplasmosis, a prevalent tick-borne infection in cattle that causes significant morbidity and an estimated $300 million in annual economic losses in the U.S. The project will test the protective capacity of outer membrane...

The U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) awarded a $599,455 Project Grant under the Small Business Innovation Research (SBIR) Program (CFDA 10.212) to VST LLC (DBA Medgene Labs) located in Brookings, SD. The purpose of this 2-year grant is to develop the first U.S.-based vaccine against the invasive Asian Longhorned Tick, which poses a major threat to animal health and productivity in cattle and other livestock. The vaccine will be...

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $270,176 to Oncosting, LLC to develop improved versions of the Bacillus Calmette-Guerin (BCG) vaccine for tuberculosis (TB). Specifically, Oncosting is engineering recombinant BCG strains, OS-101 and OS-151, to overexpress a potent STING agonist with the goal of enhancing the vaccine's protective efficacy and...

This federal Project Grant award, provided by the U.S. Department of Agriculture's National Institute of Food and Agriculture through the Agriculture and Food Research Initiative (CFDA 10.310), is funding a $800,000 effort led by the University of Pittsburgh to address the emerging threat of Influenza D virus (IDV) in cattle. The project aims to develop two critical solutions: (1) new diagnostic tests to monitor IDV in livestock, and (2) an innovative nasal spray vaccine to protect cattle from...