Project Grant 201133610307831

This Project Grant from the National Oceanic and Atmospheric Administration's Small Business Innovation Research Program totaling $150,000 will support the development of rapid diagnostic tests for the parasitic infection Amyloodinium ocellatum in fish. Live Advantage Bait, LLC dba Totally Pelagic will utilize next generation approaches to produce highly specific monoclonal antibodies for A. ocellatum dinospores and develop a lateral flow-based rapid diagnostic test. The NOAA SBIR program...

This Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Small Business Innovation Research (SBIR) Program (CFDA 10.212) provides $649,892 to Phycovax LLC to develop a novel diatom-based oral vaccine to protect fish against lactococcosis, a bacterial disease affecting trout farming in the United States. The project aims to engineer microalgae (diatoms) to produce vaccine proteins that can be incorporated into fish feed,...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $668,569 to The Schepens Eye Research Institute, Inc. to characterize and optimize a novel genetic vaccine platform called PARVAX. The key objectives are to: Investigate the mechanism behind the potency and durability of the PARVAX platform, which has demonstrated sustained immunity and protection against SARS-CoV-2...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $356,396 to William Marsh Rice University in Houston, Texas to develop vaccine formulations that exhibit exponential antigen release kinetics to enhance vaccine potency. The goal is to create a modular vaccine delivery system that can mimic the natural antigen kinetics of native infections, thereby improving the immune...

This $1,900,450 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports the advanced testing and development of a hexavalent adjuvanted influenza vaccine platform called SNAP-FLU. The award recipient, Pop Biotechnologies Inc., will produce and characterize the SNAP-FLU nanoparticle vaccine, which combines recombinant influenza hemagglutinin (HA) and neuraminidase (NA) antigens...

This two-year, $599,984 National Oceanic and Atmospheric Administration project grant supports research at the University of Maine to develop probiotic systems for sea scallop hatcheries. The goal is to enhance reliability and reproducibility of larval production throughout the year. Researchers will identify appropriate probiotic bacteria for inclusion in feed or direct addition to hatchery tanks and assess effects on larval survival and probiotic persistence. A $199,984 subaward to the...

The Department of Agriculture's National Institute of Food and Agriculture awarded $530,000 under the Agriculture and Food Research Initiative competitive grants program to develop a trivalent vaccine that protects against Marek's disease, Newcastle disease, and infectious laryngotracheitis in poultry. With a completion date of April 30, 2026, this Project Grant will fund research at the Agricultural Research Service's Southeast Area location in Stoneville, MS to design a single vaccine using...

This $300,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under CFDA 93.855 Allergy and Infectious Diseases Research supports the development of a novel immunotherapeutic fusion protein called FC3/SCR(19-20) as a pre-exposure prophylactic treatment for Rickettsia infections. The awardee, Planet Biotechnology Incorporated, is engineering and evaluating FC3/SCR(19-20) and other protein variants to enhance complement-mediated killing and phagocytosis...

This Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $7,994,888 to establish the Research and Development of Vaccines and Antibodies for Pandemic Preparedness (REVAMPP) Coordinating and Data Sharing Center (CDSC). The CDSC, led by Research Triangle Institute (RTI) International, will coordinate and facilitate a collaborative research network to accelerate the...

This federal Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under CFDA Program 93.121 Oral Diseases and Disorders Research, provides $601,354 to North Carolina State University to develop a novel method of oral cavity mucosal vaccination. The overarching goal is to establish a new paradigm in oral mucosal vaccination using dental floss coated with vaccine to target the highly permeable junctional epithelium. The research aims to: 1) comprehensively...