Project Grant 80NSSC24K0680

The National Science Foundation (NSF) awarded a $1,499,168 Cooperative Agreement under its Technology, Innovation, and Partnerships (CFDA 47.084) program to The Regents of the University of California, San Francisco (UCSF). The project aims to link UCSF's Scalable Precision Medicine Open Knowledge Engine (SPOKE) knowledge graph with NASA's GeneLab platform and incorporate social determinants of health (SDOH) data into SPOKE. This will facilitate two-way translation of knowledge and...

This $273,968 Phase I Small Business Innovation Research (SBIR) grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program supports the development of the "Space Biobank" by Rhodium Scientific LLC. This initiative aims to establish the first repository for microbial species optimized for the low-Earth orbit environment, enabling broader community engagement in space-based biotechnology research and development. The award, provided on March...

This $169,919 Project Grant award from the NASA Science Mission Directorate (CFDA 43.001 - Science) supports research to evaluate motility as an agnostic biosignature for detecting microbial life beyond Earth, such as on Mars, Europa, Enceladus, and Titan. The research, conducted through a collaboration across multiple institutions, aims to characterize biotic movement and distinguish it from non-biological movement using a combination of time-lapse light microscopy, image analysis algorithms,...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $881,303 to The Children's Hospital of Philadelphia (CHOP) to conduct high-resolution, whole genome tracking of pathogen transmission and infection in the neonatal intensive care unit (NICU). The key objectives are to use whole genome sequencing and diagnostic allele surveillance to determine bacterial transmission and...

This $907,800 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports the development of a universal bacterial genome editing platform based on phage recombinases. The University of Rochester is leading this research to create a broadly-functioning recombineering system that can edit the genomes of diverse bacterial species, including clinically-relevant pathogens. Key aspects...

This $100,000 Project Grant from the National Aeronautics and Space Administration (NASA) Shared Services Center supports research contributing to the NASA Science Mission Directorate's Science program (CFDA 43.001). Specifically, the grant funds a project conducted by Georgia Tech Research Corporation from January 2021 to January 2022. The project aims to understand the phylogeny and physiology of microorganisms with characteristics reflecting primitive environments, advancing NASA's exobiology...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to develop real-time detection methods for Staphylococcus aureus transmission in hospital settings. The $3,210,845 award to New York University aims to integrate whole-genome sequencing with weekly colonization sampling to analyze transmission dynamics and create predictive models that can...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) provides $128,655 to the University of Pittsburgh to enhance surveillance methods for genomic epidemiology in healthcare. The project aims to test the hypothesis that combining real-time whole genome sequencing (WGS) surveillance of bacterial pathogens with targeted environmental cultures will improve identification and control...

This Project Grant award from the National Aeronautics and Space Administration (NASA) Science Mission Directorate (CFDA 43.001 - Science) provides $167,311.00 to Syracuse University to research the genomic toolkit of extremophilic amoebae. The goal is to understand how these organisms adapt to harsh environments and contribute to the evolution of eukaryotes. The award period runs from July 1, 2025 to June 30, 2026. This research builds on NASA's strategic objectives to expand human knowledge...

This $400,000 Project Grant award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET), under CFDA 47.041 Engineering program, will fund The Johns Hopkins University to develop engineered heart tissue chips for testing nanoparticle-based countermeasures against spaceflight-induced heart disease. The research aims to investigate whether nanoparticles designed to scavenge reactive oxygen species can prevent mitochondrial...