Cooperative Agreement W81XWH1720062

This Project Grant award, made by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of Dermisphere, an advanced dermal regeneration scaffold product by Fesariustherapeutics Inc. The $349,345 award aims to demonstrate the feasibility of using Dermisphere to manage acute major burn wounds. Preliminary studies have shown that Dermisphere can support rapid and sustained cellular...

This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to advance the understanding of how nanogenerator-driven electrical stimulation can accelerate wound healing. The $469,766 project will investigate the cellular-level mechanisms underlying this approach and identify optimal signal and device designs to deliver the desired therapeutic effect....

This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $305,000 to LF Printech LLC, a minority-owned small business, to develop a novel bioactive hydrogel dressing with a porous surface for the treatment of second-degree burn wounds. The dressing is designed to accelerate natural healing, reduce pain and trauma associated with dressing changes, and address critical gaps in existing burn wound...

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded Panorama Research Incorporated, doing business as Panorama Research Inc., a $275,765 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to develop an antibody-based therapy for reducing scarring and fibrosis following joint surgeries. The project aims to improve the delivery and tissue residence of a lead humanized antibody that inhibits collagen fibril formation, thereby...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $2,433,408.00 to Global Biomedical Technologies LLC to develop and validate an adhesive acrylic surgical drape for use in negative pressure wound therapy (NPWT) applications. The project aims to compare the performance and clinician acceptability of the company's...

This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will provide $607,398 to Albany Medical College to conduct research on the role of epidermal integrin α3β1 in age-related changes during cutaneous wound healing. The research aims to determine how the age-related decline in the function of the α3β1 integrin in epidermal keratinocytes...

This Project Grant award of $306,324 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund research by the Oklahoma Medical Research Foundation (OMRF) to map the life cycle of myofibroblasts in skin wound healing. The project aims to create a molecular profile of how fibroblasts differentiate into myofibroblasts and then revert to a deactivated state, with a focus on...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is providing $208,125 to the University of Connecticut Health Center to develop an intralesional drug delivery strategy for treating infected wounds. The key products and services to be delivered include: Characterization of in situ formed microneedle-like drug depots and...

This Cooperative Agreement award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $536,233 to Northwestern University to develop a synthetic melanin-based treatment to accelerate wound healing and reduce scarring resulting from exposure to mustard gas. The project aims to evaluate a group of synthetic melanin particles (SMPs) for their ability to mitigate initial skin injury and promote faster wound repair...

This federal Project Grant award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), aims to develop a novel therapeutic approach to improve angiogenesis and wound healing by delivering apoptotic neutrophils within a degradable hydrogel scaffold. The $172,700 award, effective August 20, 2024 through July 31, 2026, supports research to investigate the effects of the hydrogel-apoptotic neutrophil delivery on macrophage angiogenic signaling and its impact...