Enhancing cardiovascular health equity in mothers and children through home visiting

Active Cooperative Agreement Awarded Last action

Award ID
UH3HL162970
Recipient
Awarding agency
Obligated
$4,406,419

Award facts

Assistance listing
93.361 Nursing Research
Completion date 63% complete
Funding agency
Office of the Director National Institutes of Health, Department of Health and Human Services
Place of performance
University City, MO 63130, USA

Award details come from USAspending.gov.

Description

Abstract
The foundation for cardiovascular health (CVH) is laid in early life by intergenerational interactions, passed from parent to child, that have long-lasting biological and behavioral consequences. Lifestyle interventions can promote CVH among mothers and their children over time. Academic partnerships with home visiting organizations that reach families experiencing health disparities advance intergenerational CVH equity. This study builds on a decades-long academic-home visiting partnership between the research team at washington university in ST. Louis and parents as teachers (PAT), an evidence-based home visiting program located in all 50 states. Most recently, our partnered work demonstrated the effectiveness of healthy eating and active living taught at home (health), in which we successfully tested a lifestyle intervention to promote ideal weight and CVH among pregnant and young mothers and their children. We now seek to advance this work with the enrich collaborative by rigorously testing the ongoing CVH impact of this implementation-ready approach. During the UG3 planning phase (years 1-2), we will work with the enrich collaborative to identify a common CVH protocol informed by health. In the UH3 implementation phase (years 3-7), we will rigorously test the ongoing impact on CVH of this implementation-ready approach for mothers and young children, delivered over 3 years, beginning prenatally and continuing to 30 months post- childbirth. The hybrid type 1 cluster-randomized pragmatic trial builds on this partnership (n=10 sites in high burden ST. Louis, missouri, metro region; 750 mother-child dyads; study population with one or more of the following characteristics associated with increased risk of cardiovascular disease: black or latinx, body mass index ≥ 30, and/or socioeconomic disadvantage). We will determine the effect of health on maternal CVH as assessed by a composite score on the american heart association life's simple 7 over 3 years from enrollment (before 20 weeks pregnancy) to follow-up at birth, 6, 18, and 30-months post childbirth; and on child CVH assessed by bmiz trajectory and diet, activity, sleep, and parental influence from birth to 6, 18, and 30-month follow-up. We will apply expertise in implementation science to ensure the intervention has equitable implementation and impact across PAT and the enrich collaborative. This significant study will further advance scientific understanding and evidence-based practice on how to disrupt the impact of cardiovascular risk that passes across generations to improve CVH equity. The innovation of this study is that IT will rigorously determine the impact of health on the transfer of lifestyle behaviors from mother to child, across the childbearing continuum.

Transactions

Action Obligated Date
Amendment $524,460
Amendment $62,500
Amendment $0
Amendment $0
Amendment $211,210
Amendment $211,210
Amendment $211,210
Amendment $803,858
Amendment $803,858
Amendment $62,500
Amendment Enhancing cardiovascular health in mothers and children through home visiting - this administrative supplement application in response to not-OD-24-179, will… $31,250
Amendment $1,000
Amendment Enhancing cardiovascular health in mothers and children through home visiting - this administrative supplement application in response to not-OD-24-179, will… $211,210
Amendment $30,092
Amendment $30,092
Amendment Enhancing cardiovascular health in mothers and children through home visiting - this administrative supplement application in response to not-OD-24-179, will… $318,705
Amendment $799,515
Amendment $31,250
Original award $62,500
Show all 19

Subawards

Subrecipient Amount Awarded
Barnes Jewish Hospital Scope of Work Barnes-Jewish Hospital and Dr. Sarah Farabi Specific Aims. This administrative supplement application in response to NOT-OD-24-179, will… $57,827
Barnes Jewish Hospital Scope of Work Barnes-Jewish Hospital and Dr. Sarah Farabi Project Summary The foundation for cardiovascular health (CVH) is laid in early life by… $17,158
The General Hospital Corporation Scope of Work Project Title: Enhancing Cardiovascular Health Equity in Mothers and Children Through Home Visiting Project Period: 4/01/2022-03/31/2029 Prime… $49,530
Parents AS Teachers National Center, Inc. Scope of Work Project Title: Enhancing Cardiovascular Health Equity in Mothers and Children Through Home Visiting Project Period: 4/01/2022-03/31/2029 Prime… $42,376

Quick answers

Who received award UH3HL162970?

UH3HL162970 was awarded to The Washington University by National Heart Lung and Blood Institute (National Institutes of Health) on May 5, 2022.

How much is award UH3HL162970 worth?

$4,406,419 has been obligated on UH3HL162970.

Which agency awarded UH3HL162970?

National Heart Lung and Blood Institute (National Institutes of Health) awarded UH3HL162970, with funding from Office of the Director (National Institutes of Health).

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