1/2 video telehealth pulmonary rehabilitation to reduce hospital readmission in chronic obstructive pulmonary disease (tele-copd)

Active Cooperative Agreement Awarded Last action

Award ID
UH3HL155806
Recipient
Awarding agency
Obligated
$7,895,107

Award facts

Assistance listing
93.837 Cardiovascular Diseases Research
Completion date 93% complete
Place of performance
Birmingham, AL 35294, USA

Award details come from USAspending.gov.

Description

Abstract
Acute exacerbations of chronic obstructive pulmonary disease (copd) result in significant morbidity and healthcare costs, especially severe exacerbations that require hospitalization. Traditional bronchodilators and anti- inflammatory medications, as well as programs to monitor and treat symptoms, have a modest effect on reducing hospital admissions. Readmission rates remain unacceptably high, so alternative approaches are needed. In this regard, pulmonary rehabilitation (PR) is remarkably effective, and is associated with an 80% reduction in admission rates. Successful completion of PR is also associated with substantial improvements in quality of life, dyspnea, as well as exercise tolerance. Despite these benefits, recent studies have highlighted very poor referral rates for PR overall and as low as 1.9% post-hospitalization, and non-completion rates as high as 60%. The poor adaptation of PR in the community is due to a combination of barriers in availability and accessibility, as well as attrition. The number of PR centers in the united states is inadequate, and these centers are mostly distributed in urban areas. In addition, multiple socioeconomic and medical barriers hinder access to PR, and contribute to high drop-out rates. New strategies are needed to reduce hospital readmission in copd, and to increase the delivery of PR to underserved urban as well as rural areas in the community. Given the scarcities in existing resources, conventional models of care delivery are being challenged, and attempts are being made to find alternative, cost-effective ways of delivering healthcare to a larger number of eligible patients. To overcome the socioeconomic and physical barriers to PR, we hypothesize that a video telehealth intervention that will deliver PR to the patient's home, regardless of geographic location, will reduce hospital readmissions in copd, and reduce respiratory morbidity. To test our hypothesis we propose a prospective randomized controlled phase 3 multicenter clinical trial comparing a real-time video telehealth PR intervention plus standard of care versus standard of care alone, with the following specific aims: (1) to determine if a video telehealth PR intervention reduces 30-day all-cause readmissions in patients hospitalized for acute exacerbation of copd, (2) to evaluate the effects of the video telehealth PR intervention on dyspnea and respiratory quality of life in copd post hospital discharge, and (3) to evaluate the cost-effectiveness of the telehealth intervention. Accomplishment of the aims of this study will result in a significant reduction in copd readmission rates, and a paradigm shift in the way PR is delivered to patients with copd, especially those that reside in remote and rural areas with limited access to pulmonary rehabilitation.

Transactions

Action Obligated Date
Amendment $1
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $1,767,117
Amendment $721,269
Amendment $1,802,240
Amendment $1,802,240
Original award $1,802,240

Subawards

Subrecipient Amount Awarded
The University Of Iowa 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD). $236,310
Temple University-Of The Commonwealth System Of Higher Education 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD) $40,896
Wake Forest University Health Sciences $49,045
The Cleveland Clinic Foundation $98,433
University Of Maryland, Baltimore 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD). $61,785
Northwestern University 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD) $6,738
Temple University-Of The Commonwealth System Of Higher Education $70,159
University Of Pittsburgh - Of The Commonwealth System Of Higher Education $48,659
The Feinstein Institutes For Medical Research $94,435
Baylor College Of Medicine $120,354
Healthpartners Institute $103,086
Cincinnati Education & Research For Veterans Foundation, Inc. DBA Cerv $58,734
Northwestern University $73,738
The Cleveland Clinic Foundation $88,981
Northwestern University $75,744
Healthpartners Institute $47,401
The Feinstein Institutes For Medical Research $43,694
Temple University-Of The Commonwealth System Of Higher Education $97,009
Cincinnati Education & Research For Veterans Foundation, Inc. DBA Cerv $56,135
Center For Veterans Research & Education $89,243
University Of Maryland, Baltimore 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD). $103,872
Healthpartners Institute 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD) $83,665
Baylor College Of Medicine $96,754
Healthpartners Institute $7,900
The Johns Hopkins University 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease $273,007
Boston VA Research Institute, Inc. 1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD) $275,455
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Quick answers

Who received award UH3HL155806?

UH3HL155806 was awarded to University Of Alabama At Birmingham by National Heart Lung and Blood Institute (National Institutes of Health) on September 1, 2021.

How much is award UH3HL155806 worth?

$7,895,107 has been obligated on UH3HL155806.

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