This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,553,810 to the University of Maryland, Baltimore to conduct genomic surveillance for artemisinin resistance in Africa. The project aims to identify parasite genetic adaptations and functional pathways associated with resistance to artemisinin-based combination therapies, the first-line treatment for malaria in...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) provides $128,655 to the University of Pittsburgh to enhance surveillance methods for genomic epidemiology in healthcare. The project aims to test the hypothesis that combining real-time whole genome sequencing (WGS) surveillance of bacterial pathogens with targeted environmental cultures will improve identification and control...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $881,303 to The Children's Hospital of Philadelphia (CHOP) to conduct high-resolution, whole genome tracking of pathogen transmission and infection in the neonatal intensive care unit (NICU). The key objectives are to use whole genome sequencing and diagnostic allele surveillance to determine bacterial transmission and...
This $534,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to develop wastewater surveillance systems for monitoring multidrug-resistant bacteria (MDRB). The key objectives are to: Establish standardized wastewater surveillance strategies to inform clinical infection control responses, using long-read metagenomics and novel bioinformatics to rapidly identify significant changes in...
This Project Grant award of $1,000,000 from the Fogarty International Center (CFDA 93.989 - International Research and Research Training program) supports research to understand pathogen transmission dynamics between wildlife and human settlements in rural western Uganda. The key objectives are to: 1) conduct longitudinal surveillance of adenovirus across diverse hosts and environmental sources; 2) apply advanced phylogenetic and bioinformatics analysis to model viral transmission routes; 3)...
This three-year, $240,000 project grant from the National Science Foundation will support genomic research and public education on wildlife viral emergence in Cambodia. Funded under the Biological Sciences program (CFDA 47.074), the award will enable a postdoctoral fellow to conduct metagenomic surveillance of rodents, mosquitoes, and the environment to detect known and novel viruses. Sequence data will be analyzed alongside climate and landscape data to model zoonotic spillover risk. The fellow...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $421,673 to William Marsh Rice University to develop computational tools and laboratory methods for wastewater surveillance of antimicrobial resistant pathogens. The goal is to identify signature genomic regions of antimicrobial resistant pathogens that can be specifically detected in wastewater, enabling more...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $242,310 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Trustees of Boston University's Medical Campus to establish a human intestinal organoid model for studying late-stage Ebola virus and Marburg virus infections. The project aims to characterize how these filovirus infections compromise the integrity of the intestinal epithelial barrier and disrupt ion flux, which can lead to...
This three-year, $446,377 National Science Foundation project grant supports the development of new technologies for the detection of emerging microbial threats at Purdue University. Funded through NSF's Engineering program (CFDA 47.041), the "SENTINELS: Living-Tissue for Doppler Detection of Emerging Microbial Threats" project will apply Biodynamic Doppler Profiling to detect bacterial and viral infections in living tissue samples. Researchers aim to enhance the sensitivity of the...
This Cooperative Agreement award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $4,000,000.00 in funding from February 1, 2025 to January 31, 2030 to The Broad Institute, Inc. to characterize the human virome. The project aims to develop a systematic, multimodal approach to map and understand the diversity of viruses present in humans, leveraging a cohort of 4,000 participants across the United States. Key activities include...