Neurotech harbor: our nation's first equitech ecosystem for neuromedical technologies

Active Cooperative Agreement Awarded Last action

Award ID
U54EB033664
Recipient
Awarding agency
Obligated
$92,040,757

Award facts

Assistance listing
93.279 Drug Use and Addiction Research Programs
Completion date 85% complete
Funding agency
National Institute of Neurological Disorders and Stroke National Institutes of Health, Department of Health and Human Services
Place of performance
Baltimore, MD 21218, USA

Award details come from USAspending.gov.

Description

Abstract
Overall the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions, and (aim 2) to increase the number of women & URM innovators through outreach and education, and to improve equity and accessibility of neuromedical solutions. Neurotech harbor (NTH), led by johns hopkins and howard universities, will accelerate the development of highly promising solutions to improve neurological health for all. Solutions for all means also for the underserved, often synonymous with minority groups. Diverse innovators should SIT at the table on day one, but very few minority entrepreneurs exist. To address these inequities, we will build NTH with an equitech philosophy, which is the belief that diversity of teams, leadership, and perspectives is a force multiplier to fuel innovation, producing solutions accessible to all communities. Hopkins & howard are uniquely positioned to realize this vision. Hopkins brings a foundation of researchers, prestigious research centers, and programs and has a translation track record ($3B invested in start-UPS in the last 7 years). Howard complements this with a large pipeline of aspiring under-represented minority (URM) innovators both within and outside the howard community. Howard has nurtured this community with early-stage mentorship, a successful incubator program, and recently received a $17M grant to create a center for entrepreneurship aimed at building resources and support for black business owners across the country. NTH will solicit proposals from innovators nationwide addressing pressing problems. Although the areas supported will be broad, covering all participating NIH institutes and centers, the expertise of NTH will be inclusive but focusing on neuroprosthesis (cortical, spinal, peripheral, vision, and auditory), brain machine interface, neuro sensors and devices, neuro informatics, neuromodulation, and mental health. For funded projects, resources will be provided, and a dream team of specialists will offer mentorship and tools to guide successful translation to first-in-human prototype. Specialists will be drawn from a diverse steering committee, advisory board, and consultant network, composed of highly regarded clinicians, scientists, technologists, commercialization experts, and patient advocates. To expand diversity amongst innovators, NTH has formed strategic outreach partnerships with access to historically black colleges and universities and minority serving institutions across the nation. We have created an NTH institute, a center for innovator leadership development to educate innovators in business development, translation and project management. Importantly, our needs assessments will be guided by the principles of equity and accessibility for all communities and will include the input of underserved stakeholders. Our 5-year goals are to (i) solicit over 500 applications and launch 45 projects, where at least 15 have 1 woman or URM innovator on the team, and (II) blaze a trail to alleviate suffering from neurological conditions for all, including the underserved...the equitech way.

Transactions

Action Obligated Date
Amendment $1,164,249
Amendment $944,263
Amendment $962,180
Amendment $784,069
Amendment $958,043
Amendment $1,494,862
Amendment $99,894
Amendment $951,825
Amendment $106,693
Amendment $44,071
Amendment $1,279,205
Amendment $999,999
Amendment $500,000
Amendment $105,929
Amendment $1,499,888
Amendment Neurotech harbor: optimizer #18406 - project 18406 project summary abstract chronic migraine (CM) pain is among the top 3 most burdensome disorders in the world… $1,000,000
Amendment $1,000,000
Amendment $0
Amendment Neurotech harbor - the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions, and (aim 2) to… $0
Amendment Neurotech harbor: optimizer #18406 - project 18406 project summary abstract chronic migraine (CM) pain is among the top 3 most burdensome disorders in the world… $0
Amendment Neurotech harbor - the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions, and (aim 2) to… $106,248
Amendment Neurotech harbor: optimizer #18406 - project 18406 project summary abstract chronic migraine (CM) pain is among the top 3 most burdensome disorders in the world… $106,248
Amendment Neurotech harbor - 21719 $106,248
Amendment Neurotech harbor - the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions, and (aim 2) to… $106,248
Amendment $1,196,697
Amendment $1,196,697
Amendment $1,085,775
Amendment $1,085,775
Amendment $1,360,375
Amendment $1,360,375
Amendment $561,750
Amendment $561,750
Amendment $1,950,000
Amendment $1,950,000
Amendment $1,126,307
Amendment $1,126,307
Amendment $2,366,379
Amendment $2,366,379
Amendment $1,508,290
Amendment $1,508,290
Amendment $1,414,920
Amendment $1,414,920
Amendment $500,000
Amendment $1,081,751
Amendment $1,000,000
Amendment Neurotech harbor: optimizer #20387 - the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions,… $1,000,000
Amendment Neurotech harbor - the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions, and (aim 2) to… $1,000,000
Amendment Neurotech harbor: optimizer #20387 - the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions,… $0
Amendment Neurotech harbor - the two aims of neurotech harbor are: (aim 1) to accelerate early development of the most promising neuromedical solutions, and (aim 2) to… $0
Amendment $0
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Subawards

Subrecipient Amount Awarded
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Underactive bladder is a debilitating condition characterized by an impaired ability to empty the bladder due to dysfunctional detrusor muscle contractions… $99,179
Quantum Nanostim LLC This project proposes to develop a Closed-Loop Omnidirectional, Neuromodulation with Electromagnetic fields (CLONE) spinal cord stimulation (SCS) system to… $99,943
Autonomus Medical Technologies, Inc. Hip fractures are a leading cause of morbidity and mortality among older adults, with over 300,000 U.S. cases annually [1]. Despite strong evidence supporting… $1,112,413
Launchport, LLC The LaunchPortâ„¢ (www.thelaunchport.com) is a Medical Device Manufacturing Venture Center and Contract Manufacturing operation in Baltimore, Maryland… $977,711
Arizona State University The pathway to early feasibility studies by the end of our 4-year effort will be through significant development (hardware and software) and testing efforts. We… $1,393,750
Reneu Inc. Walking impairment after stroke and other neurological injuries often persists long after conventional rehabilitation ends, limiting independence, physical… $1,284,999
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Fetal aqueductal stenosis (AS) is one of the most common cause of congenital hydrocephalus, which increases intracranial pressure due to partial or complete… $1,443,676
Battelle Memorial Institute to develop the CL�TPT System by simplifying & improving the design of Battelle’s current NeuroLife Sleeve, then integrating the updated design… $2,385,975
Praana, Inc. We propose a compact, flexible, low-cost, portable Time-of-Flight Positron Emission Tomography (TOF-PET) system to enable accessible, confirmatory imaging for… $93,144
Craniosense, Inc. The device under development at CranioSense, is noninvasive, easy to apply and interpret by non-neurologists, and capable of providing screening and… $1,146,653
Musclemetrix LLC Current prosthetic technology can make it difficult for amputees to perform common everyday tasks such as uneven terrain ambulation or hand manipulation of… $1,125,000
National Collegiate Inventors & Innovators Alliance, Inc. VentureWell will support JHU’s NeuroTech Harbor, to catalyze the creation of groundbreaking solutions for disorders involving the nervous system.… $9,073,183
Aneuvas Technologies Inc. We propose to assess and optimize the balloon-stent prototype for aneurysm endovascular treatment by utilizing resources to meet/exceed the acceptable testing… $2,586,080
Actiox LLC AUD affects ~28–29 million U.S. adults and drives ~$249–300B in annual costs. Despite this burden, clinicians and researchers lack a discreet, continuous way to… $99,498
Howard University Howard University will conduct outreach, including solicitations, educational/workshop activities, and assessment of outcomes, will provide training/mentoring… $3,996,523
Micro-Leads Inc. We will accelerate the development of our breakthrough MANTA bioelectronic stimulator. Our proprietary MANTA device self-expands after a 13-gauge… $1,305,018
Trustees Of Boston University Deficits in the force-generating ability of the muscles used to propel the body from step-to-step often never resolve after neurological injury. Consequently,… $2,529,704
Endovascular Horizons, Inc. The project will be a three year endeavor to achieve three specific aims to develop and prove the Embodrain system which includes a perforation wire and… $1,660,542
Blackrock Microsystems, Inc. BlackRock is developing a novel subcutaneous intersectional electrical stimulation (SIES) implant for the termination of seizures in drug resistant epileptic… $404,965
Open Water Internet, Inc. Prior to FDA approval and commercial launch, the subsystems such as the driving electronics and the neuro navigation system must be redesigned for low cost at… $330,000
Secondwave Systems Inc. Optimization of Neurostimulator SecondWave shall optimize the ultrasonic efficiency of the implant for receiving acoustic energy and conversion to electrical… $1,640,668
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Quick answers

Who received award U54EB033664?

U54EB033664 was awarded to The Johns Hopkins University by National Institute of Biomedical Imaging and Bioenginering (National Institutes of Health) on September 30, 2022.

How much is award U54EB033664 worth?

$92,040,757 has been obligated on U54EB033664.

Which agency awarded U54EB033664?

National Institute of Biomedical Imaging and Bioenginering (National Institutes of Health) awarded U54EB033664, with funding from National Institute of Neurological Disorders and Stroke (National Institutes of Health).

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