Anvil clinical environment for innovation and translation (ACE-IT)

Active Cooperative Agreement Awarded Last action

Award ID
U24HG013233
Recipient
Awarding agency
Obligated
$7,666,671

Award facts

Assistance listing
93.172 Human Genome Research
Completion date 59% complete
Originally
Place of performance
Nashville, TN 37203, USA

Award details come from USAspending.gov.

Description

Abstract
The analysis, visualization, and informatics lab-space (ANVIL) platform is a scalable cloud-based computing resource that aims to accelerate genomics research by providing broad access to genomics datasets and the infrastructure necessary to improve analysis workflows and enhance collaboration. The ANVIL clinical environment for innovation and translation (ACE-IT) project will bring together a network of expertise to address a major GAP in clinical genomics research and operationalize a key mission of the ANVIL project by expanding its existing ecosystem to include a comprehensive suite of clinical genomics research tools and services. The newly developed ANVIL clinical resource will bring together data, tools, and support resources meant to amplify the benefits of the existing platform and provide a critical foundation for the clinical genomics research community to better leverage this innovative resource. Development of the ACE-IT will be guided by three key aims: 1. Engagement with diverse community and research partners to characterize barriers and facilitators to adopting federally- supported, cloud-connected clinical genomics research services; 2. Development and deployment approaches to ingest, index, and search data to support clinical genomics research with an emphasis on populations historically underrepresented in biomedical research; and 3. Integration of tools, apis, and workflows that enable clinical genomics research methods on the ANVIL, including rare disease diagnosis and genomic risk scores as use cases. The ACE-IT team consists of expertise across multiple health care centers, including vanderbilt university medical center, brigham and women's hospital, massachusetts general hospital, and the american heart association. This team will develop infrastructure on ANVIL's cloud environment to meet clinical genomics researchers' needs over time and integrate with existing ANVIL working groups and meetings as team members and stakeholders where appropriate. The tools and resources we develop will support clinical genomics research by focusing on both rare and common diseases and integration into translational research.

Transactions

Action Obligated Date
Amendment $1,429,420
Amendment $0
Amendment ANVIL clinical environment for innovation and translation (ACE-IT) - the analysis, visualization, and informatics lab-space (ANVIL) platform is a scalable… $0
Amendment $1,424,502
Amendment Anvil clinical environment for innovation and translation (ACE-IT): supplement for clinical data integration meeting $164,794
Amendment $164,794
Amendment $1,494,387
Amendment $1,494,387
Original award $1,494,387

Subawards

Subrecipient Amount Awarded
The General Hospital Corporation AnVIL Clinical Environment for Innovation and Translation (ACE-IT) $330,682
Brigham & Womens Hospital Inc. $324,272
Brigham & Womens Hospital Inc. $324,273
The General Hospital Corporation $330,105
Brigham & Womens Hospital Inc. $324,271
The General Hospital Corporation $328,784
American Heart Association, Inc. $177,223

Quick answers

Who received award U24HG013233?

U24HG013233 was awarded to Vanderbilt University Medical Center by National Human Genome Research Institute (National Institutes of Health) on August 21, 2023.

How much is award U24HG013233 worth?

$7,666,671 has been obligated on U24HG013233.

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