The global alliance for genomics and health: setting the standards for genomics and health-related data sharing
Active Cooperative Agreement Awarded Last action
- Award ID
- U24HG011025
- Recipient
-
The Broad Institute, Inc. UEI H5G9NWEFHXN4
- Awarding agency
-
National Human Genome Research Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $12,920,456
Award facts
- Assistance listing
- 93.310 Trans-NIH Research Support
- Completion date 96% complete
- Originally
- Funding
-
- $12,620,456.00 Federal
- $300,000.00 Non-federal
- Place of performance
- Cambridge, MA 02142, USA
Award details come from USAspending.gov.
Description
- Abstract
- The decreasing cost of genomic sequencing will yield millions of samples in the coming years from both research and healthcare. Sharing this data is necessary to understand human diseases and eventually help patients, but doing so requires the community to agree on common methods for collecting, storing, transferring, accessing, and analyzing data. This proposal will support the global alliance for genomics and health (GA4GH; WWW.GA4GH.ORG) to aid genomic research and human health by developing standards and policies for effective and responsible data sharing between institutions and countries around the world. To advance responsible sharing of global genomic and health-related data, genomics researchers, clinicians, bioinformaticians, software engineers, and industry experts will work together as a single GA4GH community to deliver genomic data sharing standards and frameworks (e.g., ontologies, guidelines, technical schemas). Building on our five years of experience convening stakeholders and developing work products, we will engage the genomics and health community in the very earliest stages of development to ensure our work is useful and ready for adoption. We will leverage the combined effort of several hundred active contributors to advance development activities beyond the capacity of our small staff team. These contributors will work within eight GA4GH work streams, each focused on developing critical standards and frameworks, including cloud-based data federation, scalable schemas and interfaces, data models, and file formats. We will engage deeply within the broader healthcare, research, and commercial sectors, including the launch of the genomics in health implementation forum to drive uptake in the clinical domain. A federated ecosystem for searching, discovering, exchanging, and analyzing genomic and clinical data will enable a global learning health system that advances both research and clinical care beyond their individual capacities and depends on standards and interoperable frameworks embraced by the entire community. We envision a future in which the full suite of GA4GH standards enables all clinicians, geneticists, and researchers to search across the world's collective genomic data to reveal unanticipated gene-disease associations, make otherwise impossible drug-response predictions, and generally participate in genomics at a competitive pace-regardless of their means or location. The promise of genomic medicine lies at a crossroads that depends on harmonization across the community and will significantly enhance the human experience if we succeed. We believe that GA4GH is necessary to that success.
Transactions
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Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Ontario Institute For Cancer Research Institut Ontarien De Recherche SUR LE Cancer | $126,737 | |
| Genome Research LIMITED | $49,117 | |
| European Molecular Biology Laboratory | $43,200 | |
| Genome Research LIMITED | $54,882 |
Quick answers
Who received award U24HG011025?
U24HG011025 was awarded to The Broad Institute, Inc. by National Human Genome Research Institute (National Institutes of Health) on February 5, 2021.
How much is award U24HG011025 worth?
$12,920,456 has been obligated on U24HG011025: $12,620,456 in federal funding and $300,000 in non-federal funding.
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